Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C19 | P33261 | 1/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.53 |
| ▸ | CXCR4 | P61073 | 1/20 | 0.49 |
| ▸ | FABP1 | P07148 | 1/20 | 0.47 |
| ▸ | FABP6 | P51161 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | APP | P05067 | 2/20 | 0.42 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.41 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.41 |
| ▸ | ITGAV | P06756 | 1/20 | 0.41 |
| ▸ | ITGB5 | P18084 | 1/20 | 0.41 |
| ▸ | ITGB6 | P18564 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3647775 | 0.82 | POLB (0.60) | CYP2C19CYP1A2CXCR4FABP1FABP6 | |
| SCHEMBL29980727 | 0.82 | POLB (0.60) | CYP2C19CYP1A2CXCR4FABP1FABP6 | |
| SCHEMBL13628674 | 0.82 | CYP2C19 (0.51) | CYP2C19CYP1A2CXCR4FABP1FABP6 | |
| SCHEMBL3265804 | 0.79 | CYP1A2 (0.70) | CYP2C19CYP1A2CXCR4FABP1FABP6 | |
| SCHEMBL1344396 | 0.78 | CYP2C19 (0.62) | CYP2C19CYP1A2CXCR4FABP1FABP6 | |
| Hydrochloric Acid SCHEMBL8177967 | 0.77 | CYP2C19 (0.61) | CYP2C19CYP1A2CXCR4FABP1FABP6 | |
| SCHEMBL31015708 | 0.76 | CYP2C19 (0.65) | CYP2C19CYP1A2CXCR4FABP1FABP6 | |
| SCHEMBL20655751 | 0.76 | CYP1A2 (0.61) | CYP2C19CYP1A2CXCR4FABP1FABP6 | |
| SCHEMBL327850 | 0.76 | CYP2C19 (0.65) | CYP2C19CYP1A2CXCR4FABP1FABP6 | |
| SCHEMBL12954631 | 0.76 | DRD2 (0.54) | CYP2C19CYP1A2GAAKDM4EITGB3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7612197-B2 | Reacting a nucleophil with OH group with an electrophil to form an adduct, reacting adduct with a reagent selected from oxidizing, sulfurizing or selenizing agents to produce hydroxy protected oligonucleotide, heating to deprotect hydroxy protecting group such as 2-(2-pyridyl)aminoethoxycarbonyl | The United States of America as repesented by the Secretary of the Department of Health and Human Services (US) | 2009-11-03 | — | — | US | disclosed |