Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C19 | P33261 | 1/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | CXCR4 | P61073 | 1/20 | 0.45 |
| ▸ | ITGB3 | P05106 | 2/20 | 0.44 |
| ▸ | ITGAV | P06756 | 2/20 | 0.44 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.44 |
| ▸ | ITGB5 | P18084 | 1/20 | 0.44 |
| ▸ | ITGB6 | P18564 | 1/20 | 0.44 |
| ▸ | FABP1 | P07148 | 1/20 | 0.44 |
| ▸ | FABP6 | P51161 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | FDPS | P14324 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | PCSK9 | Q8NBP7 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | HTR7 | P34969 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13628532 | 0.82 | CYP2C19 (0.56) | CYP2C19CYP1A2CXCR4ITGB3ITGAV | |
| SCHEMBL3647775 | 0.78 | POLB (0.60) | CYP2C19CYP1A2CXCR4FABP1FABP6 | |
| SCHEMBL29980727 | 0.78 | POLB (0.60) | CYP2C19CYP1A2CXCR4FABP1FABP6 | |
| SCHEMBL24485296 | 0.77 | CYP2C19 (0.57) | CYP2C19CYP1A2CXCR4ITGB3ITGAV | |
| SCHEMBL3265804 | 0.75 | CYP1A2 (0.70) | CYP2C19CYP1A2CXCR4FABP1FABP6 | |
| SCHEMBL317566 | 0.75 | ALDH1A1 (0.60) | CYP2C19CYP1A2CXCR4ITGB3ITGAV | |
| SCHEMBL18233631 | 0.74 | CYP2C19 (0.54) | CYP2C19CYP1A2CXCR4ITGB3ITGAV | |
| SCHEMBL13365309 | 0.74 | CYP2C19 (0.50) | CYP2C19CYP1A2CXCR4ITGB3ITGAV | |
| SCHEMBL28657675 | 0.72 | CYP2C19 (0.56) | CYP2C19CYP1A2CXCR4ITGB3ITGAV | |
| SCHEMBL7442415 | 0.72 | CYP2C19 (0.56) | CYP2C19CYP1A2CXCR4ITGB3ITGAV |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7612197-B2 | Reacting a nucleophil with OH group with an electrophil to form an adduct, reacting adduct with a reagent selected from oxidizing, sulfurizing or selenizing agents to produce hydroxy protected oligonucleotide, heating to deprotect hydroxy protecting group such as 2-(2-pyridyl)aminoethoxycarbonyl | The United States of America as repesented by the Secretary of the Department of Health and Human Services (US) | 2009-11-03 | — | — | US | disclosed |