Known targets — ChEMBL curated mechanism
rplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Stearic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR84 | Q9NQS5 | 7/20 | 0.94 |
| ▸ | PPARG | P37231 | 7/20 | 0.94 |
| ▸ | PPARD | Q03181 | 7/20 | 0.94 |
| ▸ | PPARA | Q07869 | 7/20 | 0.94 |
| ▸ | HDAC11 | Q96DB2 | 5/20 | 0.94 |
| ▸ | TSHR | P16473 | 4/20 | 0.94 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.94 |
| ▸ | FABP4 | P15090 | 3/20 | 0.94 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.94 |
| ▸ | TLR2 | O60603 | 2/20 | 0.94 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.94 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.94 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.94 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.94 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.94 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.94 |
| ▸ | MEN1 | O00255 | 1/20 | 0.94 |
| ▸ | ESR1 | P03372 | 1/20 | 0.94 |
| ▸ | PDE4A | P27815 | 1/20 | 0.94 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.94 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Heptanoate SCHEMBL267660 | 1.00 | GPR84 (0.94) | GPR84PPARGPPARDPPARAHDAC11 | |
| Stearic Acid SCHEMBL1546700 | 1.00 | GPR84 (0.94) | GPR84PPARGPPARDPPARAHDAC11 | |
| Hexacosanoic Acid SCHEMBL2411058 | 1.00 | GPR84 (0.94) | GPR84PPARGPPARDPPARAHDAC11 | |
| Nonanoate SCHEMBL9296760 | 1.00 | GPR84 (0.94) | GPR84PPARGPPARDPPARAHDAC11 | |
| Dodecanoate SCHEMBL517385 | 1.00 | GPR84 (0.94) | GPR84PPARGPPARDPPARAHDAC11 | |
| Stearic Acid SCHEMBL455912 | 1.00 | GPR84 (0.94) | GPR84PPARGPPARDPPARAHDAC11 | |
| Stearic Acid SCHEMBL936 | 1.00 | GPR84 (0.94) | GPR84PPARGPPARDPPARAHDAC11 | |
| Palmitic Acid SCHEMBL103018 | 1.00 | GPR84 (0.94) | GPR84PPARGPPARDPPARAHDAC11 | |
| Nonadecanoic Acid SCHEMBL11324243 | 1.00 | GPR84 (0.94) | GPR84PPARGPPARDPPARAHDAC11 | |
| Stearic Acid SCHEMBL1292241 | 1.00 | GPR84 (0.94) | GPR84PPARGPPARDPPARAHDAC11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 317 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4391837-A1 | SODIUM BICARBONATE NUTRITIONAL SUPPLEMENT | Laminaria Group AB (SE) | 2024-07-03 | — | — | EP | claimed |
| EP-4346807-A1 | METHODS OF USE OF PPAR AGONIST COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS THEREOF | Astellas Pharma Inc. (JP) | 2024-04-10 | — | — | EP | claimed |
| CN-117783325-A | Method for detecting content of calcium stearate/magnesium in preparation by ion chromatography | 湖北广济药业股份有限公司 | 2024-03-29 | — | — | CN | claimed |
| US-20230082078-A1 | SODIUM BICARBONATE NUTRITIONAL SUPPLEMENT | LAMINARIA GROUP AB (SE) | 2023-03-16 | — | — | US | claimed |
| WO-2023025806-A1 | SODIUM BICARBONATE NUTRITIONAL SUPPLEMENT | LAMINARIA GROUP AB (SE) | 2023-03-02 | — | — | WO | claimed |
| WO-2022256540-A1 | METHODS OF USE OF PPAR AGONIST COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS THEREOF | ASTELLAS PHARMA INC. (JP) | 2022-12-08 | — | — | WO | claimed |
| CN-112715935-A | Pilose antler buccal tablet and preparation method thereof | 苏州红冠庄国药股份有限公司 | 2021-04-30 | — | — | CN | claimed |
| CN-111978887-A | Paste formula suitable for centralized glue making of corrugated paper | 常熟市宏华外贸包装有限责任公司 | 2020-11-24 | — | — | CN | claimed |
| CN-110419722-A | A kind of Root of Asparagus officinalis chewable tablets and preparation method thereof | UNIV QILU TECHNOLOGY | 2019-11-08 | — | — | CN | claimed |
| CN-110372341-A | A kind of ramming mass type slag runner dam | 武汉市科达耐火有限责任公司 | 2019-10-25 | — | — | CN | claimed |
| CN-1676126-A | Method for preparing anticancer, cancer-preventing ocean active medicine | UNIV QINGDAO (CN) | 2005-10-05 | — | — | CN | claimed |
| CN-1660123-A | Sustained release preparation for treating cardiovascular diseases, adn preparation method, quality control method | PHARMACEUTICAL FACTORY TONGREN (CN) | 2005-08-31 | — | — | CN | claimed |
| CN-1216603-C | Nitroimiazoles colon target medicine and its preparing process | CHINESE MEDICINE RES AND DEV C (CN) | 2005-08-31 | — | — | CN | claimed |
| CN-1562051-A | Clarithromycin controlled release tablet and taking and manufacturing method thereof | BAIWEN TECH CO LTD ZHONGSHAN (CN) | 2005-01-12 | — | — | CN | claimed |
| CN-1506094-A | Elsholizia extract granule for treating diarrhea and its prepn | 张瑞祥 | 2004-06-23 | — | — | CN | claimed |
| CN-1062590-C | Composite heavy oil comburant and its preparation | GAOKE INST OF APPLIED TECHNOLO (CN) | 2001-02-28 | — | — | CN | claimed |
| CN-1263146-A | Mosquito-expelling bactericidal propolis medicated soap | QI YONGYAN (CN) | 2000-08-16 | — | — | CN | claimed |
| CN-1222561-A | Composite heavy oil comburant and its preparation | GAOKE INST OF APPLIC TECHNOLOG (CN) | 1999-07-14 | — | — | CN | claimed |
| CN-1032732-C | Method for preparing high-nutrient prawn calcium tablet | JIA WENCHENG (CN) | 1996-09-11 | — | — | CN | claimed |
| CN-1084067-A | The manufacture method of high nutritious sea crab Ca tablet | JIA WENCHENG (CN) | 1994-03-23 | — | — | CN | claimed |