Known targets — ChEMBL curated mechanism
rplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Stearic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR84 | Q9NQS5 | 7/20 | 0.94 |
| ▸ | PPARG | P37231 | 7/20 | 0.94 |
| ▸ | PPARD | Q03181 | 7/20 | 0.94 |
| ▸ | PPARA | Q07869 | 7/20 | 0.94 |
| ▸ | HDAC11 | Q96DB2 | 5/20 | 0.94 |
| ▸ | TSHR | P16473 | 4/20 | 0.94 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.94 |
| ▸ | FABP4 | P15090 | 3/20 | 0.94 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.94 |
| ▸ | TLR2 | O60603 | 2/20 | 0.94 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.94 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.94 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.94 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.94 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.94 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.94 |
| ▸ | MEN1 | O00255 | 1/20 | 0.94 |
| ▸ | ESR1 | P03372 | 1/20 | 0.94 |
| ▸ | PDE4A | P27815 | 1/20 | 0.94 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.94 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Heptanoate SCHEMBL267660 | 1.00 | GPR84 (0.94) | GPR84PPARGPPARDPPARAHDAC11 | |
| Stearic Acid SCHEMBL1546700 | 1.00 | GPR84 (0.94) | GPR84PPARGPPARDPPARAHDAC11 | |
| Hexacosanoic Acid SCHEMBL2411058 | 1.00 | GPR84 (0.94) | GPR84PPARGPPARDPPARAHDAC11 | |
| Nonanoate SCHEMBL9296760 | 1.00 | GPR84 (0.94) | GPR84PPARGPPARDPPARAHDAC11 | |
| Dodecanoate SCHEMBL517385 | 1.00 | GPR84 (0.94) | GPR84PPARGPPARDPPARAHDAC11 | |
| Stearic Acid SCHEMBL936 | 1.00 | GPR84 (0.94) | GPR84PPARGPPARDPPARAHDAC11 | |
| Palmitic Acid SCHEMBL103018 | 1.00 | GPR84 (0.94) | GPR84PPARGPPARDPPARAHDAC11 | |
| Nonadecanoic Acid SCHEMBL11324243 | 1.00 | GPR84 (0.94) | GPR84PPARGPPARDPPARAHDAC11 | |
| Stearic Acid SCHEMBL1362870 | 1.00 | GPR84 (0.94) | GPR84PPARGPPARDPPARAHDAC11 | |
| Stearic Acid SCHEMBL1292241 | 1.00 | GPR84 (0.94) | GPR84PPARGPPARDPPARAHDAC11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 44 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107890112-A | A kind of idesia lozenge and preparation method thereof | 四川薏沅生物科技有限公司 | 2018-04-10 | — | — | CN | claimed |
| CN-107641593-A | A kind of differential plant transgenosis and non-transgenic device and method | 南通科技职业学院 | 2018-01-30 | — | — | CN | claimed |
| CN-107536817-A | A kind of dapoxetine hydrochloride pharmaceutical composition | 康普药业股份有限公司 | 2018-01-05 | — | — | CN | claimed |
| CN-107503500-A | A kind of manufacture craft of fiber drum brush | 枣庄正和制刷有限公司 | 2017-12-22 | — | — | CN | claimed |
| CN-106880614-A | A kind of Naproxen Sustained Release Tablet and preparation method thereof | 地奥集团成都药业股份有限公司 | 2017-06-23 | — | — | CN | claimed |
| CN-106867378-A | A kind of tack oil resistant wallpaper high and preparation method thereof | 安徽易有墙纸有限公司 | 2017-06-20 | — | — | CN | claimed |
| CN-106579364-A | Health food with functions of enhancing immunity and relieving physical fatigue and preparation method of health food | 江西济民可信药业有限公司 | 2017-04-26 | — | — | CN | claimed |
| CN-106215020-A | A kind of pharmaceutical composition of whitening and speckle dispelling and its preparation method and application | 南京禾宇化工有限公司 | 2016-12-14 | — | — | CN | claimed |
| CN-106188753-A | A kind of polyethylene insulation computer cable | 张翔 | 2016-12-07 | — | — | CN | claimed |
| CN-106071807-A | A kind of Quinoa health care buccal tablets and preparation method thereof | 河南科技大学 | 2016-11-09 | — | — | CN | claimed |
| CN-105906990-A | Antistatic thermal-insulation pipe and preparation method thereof | 贵州德江韫韬科技有限责任公司 | 2016-08-31 | — | — | CN | claimed |
| CN-102048656-A | Baking powder and preparation method thereof | ZHEJIANG MEIXUE COSMETIC CO LTD | 2011-05-11 | — | — | CN | claimed |
| CN-101332190-A | Sugar-free type citrulline effervescence tablet and preparation method thereof | BEIJING JIANJIANKANGKANG BIOLO (CN) | 2008-12-31 | — | — | CN | claimed |
| CN-1296049-C | Sustained release preparation for treating cardiovascular diseases, adn preparation method, quality control method | PHARMACEUTICAL FACTORY TONGREN (CN) | 2007-01-24 | — | — | CN | claimed |
| CN-1660123-A | Sustained release preparation for treating cardiovascular diseases, adn preparation method, quality control method | PHARMACEUTICAL FACTORY TONGREN (CN) | 2005-08-31 | — | — | CN | claimed |
| CN-111044624-B | Quality detection method of Chinese medicinal preparation | 广州白云山中一药业有限公司 | 2022-06-14 | — | — | CN | disclosed |
| CN-111044624-A | Quality detection method of Chinese medicinal preparation | 广州白云山中一药业有限公司 | 2020-04-21 | — | — | CN | disclosed |
| CN-1296049-C | Sustained release preparation for treating cardiovascular diseases, adn preparation method, quality control method | PHARMACEUTICAL FACTORY TONGREN (CN) | 2007-01-24 | — | — | CN | disclosed |
| CN-1660123-A | Sustained release preparation for treating cardiovascular diseases, adn preparation method, quality control method | PHARMACEUTICAL FACTORY TONGREN (CN) | 2005-08-31 | — | — | CN | disclosed |
| US-5039699-A | Powdery mixture of tocopheryl retinoate adsorbed on silicia with hydroxypropylcellulose and polyvinylpyrrolidone | LEDERLE (JAPAN), LTD. (JP) | 1991-08-13 | — | — | US | disclosed |