Stearic Acid

SCHEMBL1546700

CCCCCCCCCCCCCCCCCC(=O)O.CCCCCCCCCCCCCCCCCC(=O)O.CCCCCCCCCCCCCCCCCC(=O)O.CCCCCCCCCCCCCCCCCC(=O)O.CCCCCCCCCCCCCCCCCC(=O)O.[MgH2].[MgH2].[MgH2].[MgH2].[MgH2].[MgH2].[MgH2].[MgH2].[MgH2].[MgH2].[MgH2].[MgH2].[MgH2].[MgH2].[MgH2].[MgH2].[MgH2].[MgH2].[MgH2].[MgH2].[MgH2].[MgH2].[MgH2].[MgH2].[MgH2].[MgH2].[MgH2].[MgH2].[MgH2].[MgH2].[MgH2].[MgH2].[MgH2].[MgH2].[MgH2].[MgH2].[MgH2].[MgH2].[MgH2].[MgH2].[MgH2].[MgH2].[MgH2].[MgH2].[MgH2].[MgH2].[MgH2].[MgH2].[MgH2].[MgH2].[MgH2].[MgH2].[MgH2].[MgH2].[MgH2].[MgH2].[MgH2].[MgH2].[MgH2].[MgH2].[MgH2].[MgH2].[MgH2].[MgH2].[MgH2].[MgH2].[MgH2].[MgH2].[MgH2].[MgH2].[MgH2].[MgH2].[MgH2].[MgH2].[MgH2].[MgH2].[MgH2].[MgH2].[MgH2].[MgH2].[MgH2].[MgH2].[MgH2].[MgH2].[MgH2].[MgH2].[MgH2].[MgH2].[MgH2].[MgH2].[MgH2].[MgH2].[MgH2].[MgH2].[MgH2]

nearest known ligand 0.94

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

rplA rplB rplC rplD rplE rplF rplJ rplK rplL rplM rplN rplO rplP rplQ rplR rplS rplT rplU rplV rplW rplX rplY rpmA rpmB rpmC rpmD rpmE rpmF rpmG rpmH rpmI rpmJ rpsA rpsB rpsC rpsD rpsE rpsF rpsG rpsH rpsI rpsJ rpsK rpsL rpsM rpsN rpsO rpsP rpsQ rpsR rpsS rpsT rpsU ykgM ykgO

The experimentally established mechanism targets of Stearic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 20)

	gene	UniProt	supporting neighbours	confidence
▸	GPR84	Q9NQS5	7/20	0.94

▸	PPARG	P37231	7/20	0.94

▸	PPARD	Q03181	7/20	0.94

▸	PPARA	Q07869	7/20	0.94

▸	HDAC11	Q96DB2	5/20	0.94

▸	TSHR	P16473	4/20	0.94

▸	PTPN1	P18031	3/20	0.94

▸	FABP4	P15090	3/20	0.94

▸	ALDH1A1	P00352	2/20	0.94

▸	TLR2	O60603	2/20	0.94

▸	TDP1	Q9NUW8	2/20	0.94

▸	KMT2A	Q03164	2/20	0.94

▸	ALOX15	P16050	2/20	0.94

▸	HSD17B10	Q99714	2/20	0.94

▸	SLC22A6	Q4U2R8	1/20	0.94

▸	SLC22A8	Q8TCC7	1/20	0.94

▸	MEN1	O00255	1/20	0.94

▸	ESR1	P03372	1/20	0.94

▸	PDE4A	P27815	1/20	0.94

▸	PDE3A	Q14432	1/20	0.94

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
Heptanoate SCHEMBL267660	1.00	GPR84 (0.94)	GPR84PPARGPPARDPPARAHDAC11
Hexacosanoic Acid SCHEMBL2411058	1.00	GPR84 (0.94)	GPR84PPARGPPARDPPARAHDAC11
Nonanoate SCHEMBL9296760	1.00	GPR84 (0.94)	GPR84PPARGPPARDPPARAHDAC11
Dodecanoate SCHEMBL517385	1.00	GPR84 (0.94)	GPR84PPARGPPARDPPARAHDAC11
Stearic Acid SCHEMBL455912	1.00	GPR84 (0.94)	GPR84PPARGPPARDPPARAHDAC11
Stearic Acid SCHEMBL936	1.00	GPR84 (0.94)	GPR84PPARGPPARDPPARAHDAC11
Palmitic Acid SCHEMBL103018	1.00	GPR84 (0.94)	GPR84PPARGPPARDPPARAHDAC11
Nonadecanoic Acid SCHEMBL11324243	1.00	GPR84 (0.94)	GPR84PPARGPPARDPPARAHDAC11
Stearic Acid SCHEMBL1362870	1.00	GPR84 (0.94)	GPR84PPARGPPARDPPARAHDAC11
Stearic Acid SCHEMBL1292241	1.00	GPR84 (0.94)	GPR84PPARGPPARDPPARAHDAC11

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
EP-2311434-A1	Dry powder inhaler formulations comprising surface-modified particles with anti-adherent additives	Vectura Limited (GB)	2011-04-20	—	—	EP	disclosed