Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13628705 | 0.71 | NOTUM (0.30) | NOTUM | |
| SCHEMBL13628714 | 0.69 | IDO1 (0.32) | NOTUM | |
| SCHEMBL12091036 | 0.67 | FAAH (0.43) | NOTUM | |
| SCHEMBL13628747 | 0.66 | MAPT (0.41) | — | |
| SCHEMBL1696557 | 0.66 | NOTUM (0.68) | NOTUM | |
| SCHEMBL6629373 | 0.63 | NOTUM (0.44) | NOTUM | |
| SCHEMBL7903330 | 0.63 | NOTUM (0.70) | NOTUM | |
| SCHEMBL13848657 | 0.63 | FAAH (0.39) | NOTUM | |
| SCHEMBL1617734 | 0.63 | RAB9A (0.51) | NOTUM | |
| SCHEMBL11519618 | 0.62 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7612070-B2 | Heterocyclic compounds as antiinflammatory agents and cyclooxygenase inhibitors | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2009-11-03 | — | — | US | disclosed |
| US-7612070-B2 | Heterocyclic compounds as antiinflammatory agents and cyclooxygenase inhibitors | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2009-11-03 | — | — | US | disclosed |