SCHEMBL7192577

SCHEMBL7192577

N#Cc1c(Oc2ccc(N)cc2)cccc1Oc1ccc(N)cc1

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NCOA1 Q15788 1/20 0.49
NCOA3 Q9Y6Q9 1/20 0.49
ALDH1A1 P00352 5/20 0.48
MAPT P10636 5/20 0.48
SMN1; SMN2 Q16637 3/20 0.48
MEN1 O00255 3/20 0.48
KMT2A Q03164 3/20 0.48
GAA P10253 2/20 0.48
MITF O75030 1/20 0.48
GFER P55789 1/20 0.48
NLRP1 Q9C000 1/20 0.48
NOD2 Q9HC29 1/20 0.48
TDP1 Q9NUW8 2/20 0.48
CYP3A4 P08684 1/20 0.48
TSHR P16473 1/20 0.48
MAOA P21397 2/20 0.47
POLB P06746 2/20 0.43
TLR8 Q9NR97 2/20 0.43
KDM4E B2RXH2 1/20 0.42
NPC1 O15118 2/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30777312 0.98 NCOA1 (0.47) NCOA1NCOA3ALDH1A1MAPTSMN1; SMN2
SCHEMBL17085522 0.98 NCOA1 (0.47) NCOA1NCOA3ALDH1A1MAPTSMN1; SMN2
SCHEMBL8462720 0.98 ALDH1A1 (0.52) NCOA1NCOA3ALDH1A1MAPTSMN1; SMN2
SCHEMBL31456559 0.90 SMN1; SMN2 (0.53) NCOA1NCOA3ALDH1A1MAPTSMN1; SMN2
SCHEMBL1362882 0.90 SMN1; SMN2 (0.53) NCOA1NCOA3ALDH1A1MAPTSMN1; SMN2
SCHEMBL5012743 0.90 SMN1; SMN2 (0.53) NCOA1NCOA3ALDH1A1MAPTSMN1; SMN2
SCHEMBL17085526 0.89 ALDH1A1 (0.51) NCOA1NCOA3ALDH1A1MAPTSMN1; SMN2
SCHEMBL22169514 0.88 NCOA1 (0.42) NCOA1NCOA3ALDH1A1MAPTSMN1; SMN2
SCHEMBL1854865 0.87 ALDH1A1 (0.51) NCOA1NCOA3ALDH1A1MAPTSMN1; SMN2
SCHEMBL8466237 0.87 PARP10 (0.46) NCOA1NCOA3ALDH1A1MAPTSMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118546344-A Polyester imide, epoxy-polyester imide matrix resin, preparation method and application thereof 山东圣泉新材料股份有限公司 2024-08-27 CN claimed
CN-117327275-A High heat-resistant resin and preparation method thereof 中国人民解放军国防科技大学 2024-01-02 CN claimed
CN-115627000-B High-temperature-resistant polyimide diaphragm, preparation method thereof and application thereof in preparation of lithium ion battery 天能新能源(湖州)有限公司 2023-11-10 CN claimed
CN-116376015-A Preparation method of carborane modified phthalonitrile resin 洛阳船舶材料研究所(中国船舶集团有限公司第七二五研究所) 2023-07-04 CN claimed
CN-115627000-A High-temperature-resistant polyimide diaphragm, preparation method thereof and application thereof in preparation of lithium ion battery 天能新能源(湖州)有限公司 2023-01-20 CN claimed
CN-109593070-B Nitrile resin for high-frequency and high-speed copper-clad plate and preparation method thereof 广东汕头超声电子股份有限公司覆铜板厂 2022-05-13 CN claimed
CN-110483763-B Branched phthalonitrile resin containing benzoyl structure and preparation method thereof 大连理工大学 2022-03-29 CN claimed
CN-109705799-B YASI epoxy organic imide silica gel and preparation method thereof 东华大学 2022-03-18 CN claimed
JP-3017129-A None JP disclosed
CN-118546344-B Polyester imide, epoxy-polyester imide matrix resin, preparation method and application thereof 山东圣泉新材料股份有限公司 2026-05-19 CN disclosed
CN-118546344-A Polyester imide, epoxy-polyester imide matrix resin, preparation method and application thereof 山东圣泉新材料股份有限公司 2024-08-27 CN disclosed
CN-117510846-A Polyimide film, preparation method thereof and metallized film capacitor 南方科技大学 2024-02-06 CN disclosed
CN-117327275-A High heat-resistant resin and preparation method thereof 中国人民解放军国防科技大学 2024-01-02 CN disclosed
CN-115627000-B High-temperature-resistant polyimide diaphragm, preparation method thereof and application thereof in preparation of lithium ion battery 天能新能源(湖州)有限公司 2023-11-10 CN disclosed
CN-105273347-A Electronic heat-resisting composite material WUJIANG SHENTA QIANJIN HARDWARE FACTORY 2016-01-27 CN disclosed
US-20030064235-A1 Optical members made of polymide resins MITSUI CHEMICALS, INC. (JP) 2003-04-03 US disclosed
EP-1237015-A1 OPTICAL MEMBERS MADE OF POLYIMIDE RESINS Mitsui Chemicals, Inc. (JP) 2002-09-04 EP disclosed
US-5101005-A Improved solvent resistance, nitrile containing diamine HOECHST CELANESE CORP. (US) 1992-03-31 US disclosed
JP-H0317129-A CROSSLINKABLE POLYIMIDE FROM BIS(AMINOPHENOXY) BENZONITRILE HOECHST CELANESE CORP 1991-01-25 JP disclosed
EP-0397023-A2 Crosslinkable polyimides from bis (aminophenoxy) benzonitriles HOECHST CELANESE CORPORATION (US) 1990-11-14 EP disclosed