Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.58 |
| ▸ | POLB | P06746 | 2/20 | 0.56 |
| ▸ | GAA | P10253 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.44 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.41 |
| ▸ | RAF1 | P04049 | 1/20 | 0.41 |
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | LTA4H | P09960 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.41 |
| ▸ | LPAR5 | Q9H1C0 | 1/20 | 0.41 |
| ▸ | AR | P10275 | 4/20 | 0.41 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.41 |
| ▸ | TLR8 | Q9NR97 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9745478 | 1.00 | SMN1; SMN2 (0.58) | SMN1; SMN2KDM4EPOLBGAAMAPT | |
| SCHEMBL669346 | 0.96 | SMN1; SMN2 (0.57) | SMN1; SMN2KDM4EPOLBGAAMAPT | |
| SCHEMBL9746273 | 0.95 | SMN1; SMN2 (0.54) | SMN1; SMN2KDM4EPOLBGAAMAPT | |
| Ammonia Solution, Strong SCHEMBL28193306 | 0.95 | SMN1; SMN2 (0.56) | SMN1; SMN2KDM4EPOLBGAAMAPT | |
| SCHEMBL9746110 | 0.93 | SMN1; SMN2 (0.52) | SMN1; SMN2KDM4EPOLBGAAMAPT | |
| SCHEMBL9746326 | 0.93 | SMN1; SMN2 (0.54) | SMN1; SMN2KDM4EPOLBGAAMAPT | |
| Dimethylamine SCHEMBL1361903 | 0.90 | POLB (0.53) | SMN1; SMN2KDM4EPOLBGAAMAPT | |
| SCHEMBL9746057 | 0.88 | KDM4E (0.53) | SMN1; SMN2KDM4EPOLBGAAMAPT | |
| SCHEMBL9359794 | 0.86 | KDM4E (0.54) | SMN1; SMN2KDM4EPOLBGAAMAPT | |
| SCHEMBL20511067 | 0.86 | KDM4E (0.54) | SMN1; SMN2KDM4EPOLBGAAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5118431-A | Phthalonitriles and phthalocyanines as lubricity-enhancing additives | THE DOW CHEMICAL COMPANY (US) | 1992-06-02 | — | — | US | disclosed |
| US-5061388-A | Novel phthalonitriles and phthalocyanines as lubricity-enhancing additives | THE DOW CHEMICAL COMPANY (US) | 1991-10-29 | — | — | US | disclosed |