Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SGK1 | O00141 | 1/20 | 0.61 |
| ▸ | MEN1 | O00255 | 4/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.57 |
| ▸ | POLB | P06746 | 3/20 | 0.57 |
| ▸ | NPC1 | O15118 | 2/20 | 0.57 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.55 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | CASP3 | P42574 | 1/20 | 0.47 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.47 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13628711 | 0.83 | SGK1 (0.69) | SGK1MEN1KMT2ALMNARAB9A | |
| SCHEMBL13628792 | 0.83 | ALDH1A1 (0.58) | SGK1MEN1KMT2ANPC1TDP1 | |
| SCHEMBL14066176 | 0.81 | SGK1 (0.73) | SGK1MEN1KMT2APOLBNPC1 | |
| SCHEMBL13628786 | 0.81 | SGK1 (0.54) | SGK1MEN1KMT2APOLBNPC1 | |
| SCHEMBL13628769 | 0.81 | SGK1 (0.59) | SGK1MEN1KMT2ANPC1TDP1 | |
| SCHEMBL13628785 | 0.80 | SGK1 (0.56) | SGK1MEN1KMT2APOLBTDP1 | |
| SCHEMBL13628720 | 0.80 | SGK1 (0.65) | SGK1MEN1KMT2APOLBNPC1 | |
| SCHEMBL13628775 | 0.79 | ALOX15 (0.54) | SGK1MEN1KMT2APOLBNPC1 | |
| SCHEMBL13628766 | 0.79 | SGK1 (0.57) | SGK1MEN1KMT2ALMNAALOX15 | |
| SCHEMBL13628717 | 0.79 | SGK1 (0.73) | SGK1MEN1KMT2APOLBTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7619115-B2 | Ortho-substituted N'-benzylidene-(3-hydroxyphenyl)acethydrazides | MERCK PATENT GMBH (DE) | 2009-11-17 | — | — | US | disclosed |