Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 3/20 | 0.35 |
| ▸ | NPC1 | O15118 | 2/20 | 0.33 |
| ▸ | F2RL3 | Q96RI0 | 1/20 | 0.31 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.31 |
| ▸ | CXCR3 | P49682 | 1/20 | 0.31 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13628861 | 0.88 | RAB9A (0.38) | RAB9ANPC1P2RX7 | |
| SCHEMBL2927904 | 0.80 | PTGS2 (0.37) | RAB9ANPC1ADORA2ACXCR3GAA | |
| SCHEMBL13628824 | 0.73 | RAB9A (0.36) | RAB9ANPC1P2RX7 | |
| SCHEMBL13628819 | 0.70 | CNR1 (0.43) | RAB9AADORA2AGAA | |
| SCHEMBL13628825 | 0.69 | CYP1A2 (0.37) | — | |
| SCHEMBL13628838 | 0.69 | CYP1A2 (0.36) | ADORA2A | |
| SCHEMBL13628864 | 0.69 | CYP1A2 (0.39) | — | |
| SCHEMBL2922100 | 0.67 | CNR2 (0.42) | RAB9ANPC1 | |
| SCHEMBL2921187 | 0.58 | PTGS2 (0.44) | — | |
| SCHEMBL9159203 | 0.58 | KDM4E (0.51) | GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7612070-B2 | Heterocyclic compounds as antiinflammatory agents and cyclooxygenase inhibitors | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2009-11-03 | — | — | US | disclosed |