Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.48 |
| ▸ | PKM | P14618 | 2/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.47 |
| ▸ | PPARG | P37231 | 7/20 | 0.44 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.42 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | GMNN | O75496 | 1/20 | 0.42 |
| ▸ | EGFR | P00533 | 1/20 | 0.42 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13628675 | 0.83 | MAPT (0.46) | MAPTALDH1A1KDM4EPKMHTT | |
| SCHEMBL8129550 | 0.81 | CYP2C19 (0.51) | MAPTALDH1A1KDM4EPKMHTT | |
| SCHEMBL13662531 | 0.79 | CYP2C19 (0.49) | MAPTALDH1A1KDM4EPKMHTT | |
| SCHEMBL12788340 | 0.79 | CYP2C19 (0.49) | MAPTALDH1A1KDM4EPKMHTT | |
| SCHEMBL726956 | 0.78 | CYP2C19 (0.51) | MAPTALDH1A1KDM4EPKMHTT | |
| SCHEMBL3117237 | 0.77 | KMT2A (0.59) | MAPTALDH1A1KDM4EPKMHTT | |
| SCHEMBL13628526 | 0.77 | HRH3 (0.39) | MAPTALDH1A1KDM4EPKMHTT | |
| Hydrochloric Acid SCHEMBL27281780 | 0.77 | LMNA (0.50) | MAPTALDH1A1KDM4EPKMHTT | |
| SCHEMBL434743 | 0.75 | CYP2D6 (0.56) | MAPTALDH1A1KDM4EPKMHTT | |
| SCHEMBL4445537 | 0.75 | CYP2D6 (0.72) | MAPTALDH1A1KDM4EPKMHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7612197-B2 | Reacting a nucleophil with OH group with an electrophil to form an adduct, reacting adduct with a reagent selected from oxidizing, sulfurizing or selenizing agents to produce hydroxy protected oligonucleotide, heating to deprotect hydroxy protecting group such as 2-(2-pyridyl)aminoethoxycarbonyl | The United States of America as repesented by the Secretary of the Department of Health and Human Services (US) | 2009-11-03 | — | — | US | disclosed |