Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RORA | P35398 | 2/20 | 0.45 |
| ▸ | RORC | P51449 | 2/20 | 0.45 |
| ▸ | RORB | Q92753 | 2/20 | 0.45 |
| ▸ | CNR2 | P34972 | 3/20 | 0.41 |
| ▸ | FDFT1 | P37268 | 2/20 | 0.41 |
| ▸ | PGR | P06401 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | PLA2G4A | P47712 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | MCHR2 | Q969V1 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13932489 | 0.97 | RORA (0.44) | RORARORCRORBCNR2FDFT1 | |
| SCHEMBL13932498 | 0.94 | RORA (0.41) | RORARORCRORBCNR2FDFT1 | |
| SCHEMBL24004264 | 0.93 | RORA (0.41) | RORARORCRORBCNR2FDFT1 | |
| SCHEMBL10042901 | 0.92 | KDM4E (0.44) | RORARORCRORBPGRKDM4E | |
| SCHEMBL13932488 | 0.92 | KDM4E (0.44) | RORARORCRORBPGRKDM4E | |
| SCHEMBL14020654 | 0.90 | RORA (0.43) | RORARORCRORBCNR2PGR | |
| SCHEMBL13932547 | 0.89 | RORA (0.47) | RORARORCRORBCNR2FDFT1 | |
| SCHEMBL10067556 | 0.89 | RORA (0.47) | RORARORCRORBCNR2FDFT1 | |
| SCHEMBL13776939 | 0.89 | RORA (0.47) | RORARORCRORBCNR2FDFT1 | |
| SCHEMBL13620181 | 0.89 | HSD11B1 (0.42) | RORARORCRORBPGRPLA2G4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8343636-B2 | Crosslinkable hole-transporting materials for organic light-emitting devices | UNIVERSITY OF WASHINGTON (US) | 2013-01-01 | — | — | US | disclosed |
| US-20090278445-A1 | CROSSLINKABLE HOLE-TRANSPORTING MATERIALS FOR ORGANIC LIGHT-EMITTING DEVICES | WASHINGTON, UNIVERSITY OF (US) | 2009-11-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090278445-A1 | CROSSLINKABLE HOLE-TRANSPORTING MATERIALS FOR ORGANIC LIGHT-EMITTING DEVICES | SUN2, HTT, SLC29A1 | RORA 3497/4885RORC 3384/4885RORB 3701/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.