Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM1 | P11229 | 1/20 | 0.47 |
| ▸ | AKR1A1 | P14550 | 1/20 | 0.47 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.47 |
| ▸ | HTR2A | P28223 | 1/20 | 0.47 |
| ▸ | HTR2C | P28335 | 1/20 | 0.47 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.47 |
| ▸ | HRH1 | P35367 | 1/20 | 0.47 |
| ▸ | DRD3 | P35462 | 1/20 | 0.47 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.47 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | PPARG | P37231 | 6/20 | 0.41 |
| ▸ | PTGES | O14684 | 2/20 | 0.41 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.41 |
| ▸ | PPARA | Q07869 | 6/20 | 0.41 |
| ▸ | PPARD | Q03181 | 5/20 | 0.41 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.39 |
| ▸ | CPA3 | P15088 | 1/20 | 0.39 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4547668 | 0.81 | ALOX5 (0.40) | PPARGPTGESALOX5PPARACYP1A2 | |
| SCHEMBL4547663 | 0.78 | ANPEP (0.44) | PPARGPTGESALOX5CPA3CYP1A2 | |
| SCHEMBL29865172 | 0.77 | PPARA (0.56) | CHRM1AKR1A1CHRM3HTR2AHTR2C | |
| SCHEMBL12035903 | 0.76 | FFAR4 (0.41) | HDAC1PPARAPPARD | |
| SCHEMBL16089573 | 0.75 | SLC7A5 (0.52) | HTR2ATDP1PPARGCYP1A2 | |
| SCHEMBL12493539 | 0.74 | PPARA (0.54) | CHRM1AKR1A1CHRM3HTR2AHTR2C | |
| SCHEMBL12493992 | 0.74 | PPARA (0.54) | CHRM1AKR1A1CHRM3HTR2AHTR2C | |
| SCHEMBL4550704 | 0.74 | CYP1A2 (0.70) | CHRM1AKR1A1CHRM3HTR2AHTR2C | |
| SCHEMBL6657008 | 0.74 | CYP1A2 (0.70) | CHRM1AKR1A1CHRM3HTR2AHTR2C | |
| SCHEMBL4547656 | 0.74 | PPARA (0.43) | PPARGPTGESALOX5PPARAPPARD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090291993-A1 | Difluorophenol Derivatives and Their Use | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2009-11-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090291993-A1 | Difluorophenol Derivatives and Their Use | TPMT, FABP3, DPP4 | CHRM1 3975/4885AKR1A1 834/4885CHRM3 2839/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.