SCHEMBL4550704

SCHEMBL4550704

CCCC(Cc1ccccc1)C(=O)O

nearest known ligand 0.70

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 1/20 0.70
CPA3 P15088 3/20 0.68
FOLH1 Q04609 2/20 0.64
CPA1 P15085 7/20 0.61
CPB1 P15086 1/20 0.61
CPB2 Q96IY4 1/20 0.61
HDAC1 Q13547 2/20 0.56
HDAC2 Q92769 2/20 0.56
HDAC3 O15379 1/20 0.56
HDAC4 P56524 1/20 0.56
HDAC8 Q9BY41 1/20 0.56
SLC1A3 P43003 1/20 0.56
SLC1A2 P43004 1/20 0.56
SLC1A1 P43005 1/20 0.56
CHRM1 P11229 1/20 0.56
AKR1A1 P14550 1/20 0.56
CHRM3 P20309 1/20 0.56
HTR2A P28223 1/20 0.56
HTR2C P28335 1/20 0.56
ADRA1A P35348 1/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6657008 1.00 CYP1A2 (0.70) CYP1A2CPA3FOLH1CPA1CPB1
SCHEMBL12494702 0.96 CYP1A2 (0.66) CYP1A2CPA3FOLH1CPA1CPB1
SCHEMBL12494942 0.96 CYP1A2 (0.66) CYP1A2CPA3FOLH1CPA1CPB1
SCHEMBL7300579 0.89 FOLH1 (0.70) CYP1A2CPA3FOLH1CPA1CPB1
SCHEMBL5710051 0.89 CYP1A2 (0.59) CYP1A2CPA3FOLH1CPA1CPB1
SCHEMBL12494233 0.88 CYP1A2 (0.83) CYP1A2CPA3FOLH1CPA1CPB1
SCHEMBL19821208 0.88 CYP1A2 (0.83) CYP1A2CPA3FOLH1CPA1CPB1
SCHEMBL6724759 0.88 CYP1A2 (0.83) CYP1A2CPA3FOLH1CPA1CPB1
SCHEMBL10778624 0.87 FOLH1 (0.68) CYP1A2CPA3FOLH1CPA1CPB1
SCHEMBL27513375 0.87 FOLH1 (0.68) CYP1A2CPA3FOLH1CPA1CPB1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 36 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2529277-B1 FLEXOGRAPHIC PROCESSING SOLUTION AND USE EASTMAN KODAK CO (US) 2019-04-03 EP claimed
US-20050267168-A1 Pentanoic acid derivatives ONO PHARMACEUTICAL CO., LTD. 2005-12-01 US claimed
CN-1200703-C Use of pentanoate derivant ONO PHARMACEUTICAL CO (JP) 2005-05-11 CN claimed
US-20030096802-A1 Pentanoic acid derivatives ONO PHARMACEUTICAL CO., LTD. 2003-05-22 US claimed
US-RE37670-E1 Antiproliferative and neurotrophic molecules AMERICAN BIOGENETICS INC. 2002-04-23 US claimed
CN-1322524-A Use of pentanoate derivant ONO PHARMACEUTICAL CO (JP) 2001-11-21 CN claimed
US-6201021-B1 TREATMENT OF DISEASES INDUCED BY REACTIVE ASTROCYTES ONO PHARMACEUTICAL CO., LTD. (JP) 2001-03-13 US claimed
EP-0632008-B1 Pentanoic acid derivatives ONO PHARMACEUTICAL CO (JP) 1998-02-04 EP claimed
US-5672746-A UNSATURATED ALKYL CARBOXYLIC ACIDS(AND THEIR SALTS) FOR TREATMENT OR PREVENTION OF NERVOUS SYSTEM DISORDERS AMERICAN BIOGENETIC SCIENCES, INC. (US) 1997-09-30 US claimed
EP-0632008-A1 Pentanoic acid derivatives ONO PHARMACEUTICAL CO., LTD. (JP) 1995-01-04 EP claimed
US-20250231157-A1 METHOD FOR DETERMINING THE PARTITION OF NAPHTHENIC ACIDS FROM A PRODUCTION WATER MIMICKING SYSTEM AND MIMICKING SYSTEM PETRÓLEO BRASILEIRO S.A. – PETROBRAS (BR) 2025-07-17 US disclosed
CN-104619327-B Prodrug as the amido quinazoline of kinase inhibitor 葛兰素史密斯克莱知识产权发展有限公司 2017-03-08 CN disclosed
WO-2015134467-A1 METHODS AND COMPOSITIONS FOR DIRECT RADIOACTIVE LABELING OF BIO-ACTIVE MOLECULES AND BUILDING BLOCKS THE TRUSTEES OF PRINCETON UNIVERSITY (US) 2015-09-11 WO disclosed
US-8569058-B2 Nerve regeneration promoters ONO PHARMACEUTICAL CO., LTD. (JP) 2013-10-29 US disclosed
EP-2094662-A1 POLYCYCLIC ACID COMPOUNDS USEFUL AS CRTH2 ANTAGONISTS AND ANTIALLERGIC AGENTS Astellas Pharma Inc. (JP) 2009-09-02 EP disclosed
EP-0686155-A1 XANTHINE DERIVATIVES AS ADENOSINE A1 RECEPTOR ANTAGONISTS MERRELL PHARMACEUTICALS INC. (US) 1995-12-13 EP disclosed
WO-1994019349-A1 XANTHINE DERIVATIVES AS ADENOSINE A1 RECEPTOR ANTAGONISTS MERRELL DOW PHARMACEUTICALS INC. (US) 1994-09-01 WO disclosed
CN-1055181-A SELECTIVE ADENOSINE RECEPTOR AGENTS MERRELL DOW PHARMA (US) 1991-10-09 CN disclosed
EP-0449175-A2 Selective adenosine receptor agents MERRELL PHARMACEUTICALS INC. (US) 1991-10-02 EP disclosed
US-5047534-A Xanthine derivatives; hyupotensive agents, cardiotonic agents MERRELL DOW PHARMACEUTICALS INC. (US) 1991-09-10 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050267168-A1 Pentanoic acid derivatives FFAR3, FFAR1, HCAR3 CYP1A2 3287/4885CPA3 1989/4885FOLH1 3110/4885
US-20030096802-A1 Pentanoic acid derivatives FFAR3, FPR1, FPR3 CYP1A2 3377/4885CPA3 1028/4885FOLH1 2384/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.