Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.74 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.74 |
| ▸ | HSD11B1 | P28845 | 5/20 | 0.69 |
| ▸ | MGLL | Q99685 | 3/20 | 0.67 |
| ▸ | MEN1 | O00255 | 3/20 | 0.63 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.63 |
| ▸ | HPGD | P15428 | 1/20 | 0.63 |
| ▸ | TSHR | P16473 | 1/20 | 0.63 |
| ▸ | TEAD1 | P28347 | 1/20 | 0.61 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.53 |
| ▸ | RHOC | P08134 | 1/20 | 0.53 |
| ▸ | RHOA | P61586 | 1/20 | 0.53 |
| ▸ | L3MBTL3 | Q96JM7 | 1/20 | 0.53 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.51 |
| ▸ | UBE2M | P61081 | 2/20 | 0.51 |
| ▸ | DCUN1D1 | Q96GG9 | 2/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4526323 | 0.87 | GAA (0.76) | GAATDP1HSD11B1MGLLMEN1 | |
| SCHEMBL8280316 | 0.85 | GAA (0.69) | GAATDP1HSD11B1MGLLMEN1 | |
| SCHEMBL30964009 | 0.84 | GAA (0.73) | GAATDP1HSD11B1MGLLMEN1 | |
| SCHEMBL8537331 | 0.83 | HSD11B1 (0.74) | GAAHSD11B1MGLLMEN1KMT2A | |
| SCHEMBL5536446 | 0.83 | GAA (0.71) | GAATDP1HSD11B1MGLLMEN1 | |
| SCHEMBL23775473 | 0.82 | GAA (0.74) | GAATDP1HSD11B1MGLLMEN1 | |
| SCHEMBL1720793 | 0.82 | HSD11B1 (0.81) | GAATDP1HSD11B1MGLLMEN1 | |
| SCHEMBL13314119 | 0.81 | MGLL (0.64) | GAAHSD11B1MGLLMEN1KMT2A | |
| SCHEMBL4468382 | 0.81 | GAA (0.64) | GAATDP1HSD11B1MGLLMEN1 | |
| SCHEMBL13503768 | 0.81 | GAA (0.64) | GAATDP1HSD11B1MGLLMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7622487-B2 | Piperidine derivative, process for producing the same, and use | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2009-11-24 | — | — | US | disclosed |
| US-7622487-B2 | Piperidine derivative, process for producing the same, and use | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2009-11-24 | — | — | US | disclosed |