Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | JAK1 | P23458 | 2/20 | 0.36 |
| ▸ | JAK3 | P52333 | 2/20 | 0.36 |
| ▸ | JAK2 | O60674 | 1/20 | 0.36 |
| ▸ | TYK2 | P29597 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | CNR1 | P21554 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.34 |
| ▸ | NAMPT | P43490 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20253124 | 0.84 | FAAH (0.41) | ALDH1A1NPC1L3MBTL1GAALMNA | |
| SCHEMBL19195080 | 0.84 | L3MBTL1 (0.50) | EPHX2NPC1JAK1JAK3JAK2 | |
| SCHEMBL19195033 | 0.82 | EPHX2 (0.43) | EPHX2ALDH1A1NPC1JAK1JAK3 | |
| SCHEMBL14009820 | 0.82 | NAMPT (0.42) | ALDH1A1NPC1L3MBTL1GAALMNA | |
| SCHEMBL12385899 | 0.81 | ALDH1A1 (0.58) | EPHX2ALDH1A1NPC1LMNAMEN1 | |
| SCHEMBL13804082 | 0.79 | ALDH1A1 (0.41) | ALDH1A1NPC1L3MBTL1GAAMEN1 | |
| SCHEMBL19195034 | 0.79 | ALDH1A1 (0.61) | ALDH1A1NPC1MEN1TSHRKMT2A | |
| SCHEMBL12424441 | 0.79 | EPHX2 (0.43) | EPHX2ALDH1A1NPC1P2RY12 | |
| SCHEMBL12384790 | 0.79 | CYP2D6 (0.46) | EPHX2ALDH1A1NPC1JAK1JAK3 | |
| SCHEMBL4957159 | 0.78 | GAA (0.38) | ALDH1A1NPC1GAALMNAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7622487-B2 | Piperidine derivative, process for producing the same, and use | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2009-11-24 | — | — | US | disclosed |
| US-7622487-B2 | Piperidine derivative, process for producing the same, and use | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2009-11-24 | — | — | US | disclosed |