Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 2/20 | 0.35 |
| ▸ | PTGES | O14684 | 1/20 | 0.35 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.33 |
| ▸ | BACE1 | P56817 | 1/20 | 0.33 |
| ▸ | KIF11 | P52732 | 2/20 | 0.33 |
| ▸ | KDM1A | O60341 | 1/20 | 0.32 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.32 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.32 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.32 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | MAP2K4 | P45985 | 1/20 | 0.31 |
| ▸ | MAPK6 | Q16659 | 1/20 | 0.31 |
| ▸ | MAPKAPK5 | Q8IW41 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | FABP4 | P15090 | 1/20 | 0.31 |
| ▸ | FABP5 | Q01469 | 1/20 | 0.31 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.31 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13711341 | 0.97 | PTGES (0.34) | ALOX5PTGESTRPV1BACE1KIF11 | |
| SCHEMBL13615665 | 0.90 | KIF11 (0.40) | ALOX5PTGESTRPV1BACE1KIF11 | |
| SCHEMBL13615686 | 0.84 | TP53 (0.37) | ALOX5PTGESKIF11NR1H4HDAC6 | |
| SCHEMBL12928329 | 0.84 | TP53 (0.37) | ALOX5PTGESKIF11NR1H4HDAC6 | |
| SCHEMBL13615646 | 0.84 | TP53 (0.37) | ALOX5PTGESKIF11NR1H4HDAC6 | |
| SCHEMBL10112348 | 0.83 | KIF11 (0.44) | ALOX5BACE1KIF11KDM1ASMN1; SMN2 | |
| SCHEMBL13615656 | 0.81 | TSHR (0.41) | ALOX5PTGESKIF11TP53SMN1; SMN2 | |
| SCHEMBL12770708 | 0.81 | PTGES (0.41) | ALOX5PTGESKIF11TP53SMN1; SMN2 | |
| SCHEMBL10304794 | 0.81 | PTGES (0.37) | ALOX5PTGESKIF11NR1H4TP53 | |
| SCHEMBL10304792 | 0.80 | PTGES (0.38) | ALOX5PTGESKIF11NR1H4TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090273277-A1 | Novel organic electroluminescent compounds and organic electroluminescent device using the same | GRACEL DISPLAY INC. (KR) | 2009-11-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090273277-A1 | Novel organic electroluminescent compounds and organic electroluminescent device using the same | OCIAD1, ORMDL3, CHRM2 | ALOX5 127/4885PTGES 2165/4885TRPV1 434/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.