SCHEMBL10304792

SCHEMBL10304792

CC(C)(C)c1ccc(N(c2ccc(C(C)(C)C)cc2)c2ccc3c(-c4ccccc4)c4cc(N(c5ccc(C(C)(C)C)cc5)c5ccc(C(C)(C)C)cc5)ccc4c(-c4ccccc4)c3c2)cc1

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PTGES O14684 1/20 0.38
ALOX5 P09917 1/20 0.38
TP53 P04637 1/20 0.35
SMN1; SMN2 Q16637 1/20 0.35
KIF11 P52732 3/20 0.35
CYP2D6 P10635 2/20 0.34
GPR84 Q9NQS5 1/20 0.34
NR1H4 Q96RI1 1/20 0.33
MEN1 O00255 1/20 0.33
RAB9A P51151 1/20 0.33
KMT2A Q03164 1/20 0.33
NPSR1 Q6W5P4 1/20 0.33
ABCG2 Q9UNQ0 1/20 0.33
TNKS O95271 1/20 0.32
TNKS2 Q9H2K2 1/20 0.32
ACHE P22303 2/20 0.32
SERPINE1 P05121 1/20 0.32
KDM4E B2RXH2 1/20 0.32
ALDH1A1 P00352 1/20 0.32
CYP1A2 P05177 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10304794 0.98 PTGES (0.37) PTGESALOX5TP53SMN1; SMN2KIF11
SCHEMBL12770708 0.96 PTGES (0.41) PTGESALOX5TP53SMN1; SMN2KIF11
SCHEMBL12928329 0.95 TP53 (0.37) PTGESALOX5TP53SMN1; SMN2KIF11
SCHEMBL13615646 0.95 TP53 (0.37) PTGESALOX5TP53SMN1; SMN2KIF11
SCHEMBL13615686 0.95 TP53 (0.37) PTGESALOX5TP53SMN1; SMN2KIF11
SCHEMBL14515992 0.93 PTGES (0.37) PTGESALOX5TP53SMN1; SMN2KIF11
SCHEMBL13615816 0.92 KIF11 (0.36) PTGESALOX5TP53SMN1; SMN2KIF11
SCHEMBL13615706 0.92 PTGES (0.39) PTGESALOX5TP53SMN1; SMN2KIF11
SCHEMBL14515983 0.91 TP53 (0.33) PTGESALOX5TP53SMN1; SMN2KIF11
SCHEMBL13670041 0.91 PTGES (0.33) PTGESALOX5TP53SMN1; SMN2CYP2D6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 62 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8647753-B2 Organic electroluminescence device LG DISPLAY CO., LTD. (KR) 2014-02-11 US disclosed
US-8647753-B2 Organic electroluminescence device LG DISPLAY CO., LTD. (KR) 2014-02-11 US disclosed
EP-2182002-B1 Novel compounds for electronic material and organic electronic device using the same GRACEL DISPLAY INC (KR) 2012-07-04 EP disclosed
WO-2011051749-A1 NOVEL COMPOUNDS FOR ELECTRONIC MATERIAL AND ORGANIC ELECTRONIC DEVICE USING THE SAME GRACEL DISPLAY INC. (KR) 2011-05-05 WO disclosed
US-7906228-B2 Compounds for electronic material and organic electronic device using the same GRACEL DISPLAY INC. (KR) 2011-03-15 US disclosed
US-7906228-B2 Compounds for electronic material and organic electronic device using the same GRACEL DISPLAY INC. (KR) 2011-03-15 US disclosed
EP-2062958-B1 Novel organic electroluminescent compounds and organic electroluminescent device using the same GRACEL DISPLAY INC (KR) 2010-07-28 EP disclosed
EP-2202283-A1 Novel organic electroluminescent compounds and organic electroluminescent device using the same Gracel Display Inc. (KR) 2010-06-30 EP disclosed
WO-2010058995-A1 ELECTROLUMINESCENT DEVICE USING THE ELECTROLUMINESCENT COMPOUNDS GRACEL DISPLAY INC. (KR) 2010-05-27 WO disclosed
EP-2066150-B1 Novel red electroluminescent compounds and organic electroluminescent device using the same GRACEL DISPLAY INC (KR) 2010-05-26 EP disclosed
US-20090145483-A1 Novel electroluminescent compounds and organic electroluminescent device suing the same GRACEL DISPLAY INC. (KR) 2009-06-11 US disclosed
US-20090145483-A1 Novel electroluminescent compounds and organic electroluminescent device suing the same GRACEL DISPLAY INC. (KR) 2009-06-11 US disclosed
EP-2066150-A1 Novel red electroluminescent compounds and organic electroluminescent device using the same Gracel Display Inc. (KR) 2009-06-03 EP disclosed
EP-2062900-A1 Novel organic electroluminescent compounds and organic electroluminescent device using the same Gracel Display Inc. (KR) 2009-05-27 EP disclosed
EP-2060579-A1 Novel red electroluminescent compounds and organic electroluminescent device using the same Gracel Display Inc. (KR) 2009-05-20 EP disclosed
EP-2058322-A2 Novel red electroluminescent compounds and organic electroluminescent device using the same Gracel Display Inc. (KR) 2009-05-13 EP disclosed
EP-2055710-A1 Novel organic electroluminescent compounds and organic electroluminescent device using the same Gracel Display Inc. (KR) 2009-05-06 EP disclosed
EP-2055709-A2 Novel red electroluminescent compounds and organic electroluminescent device using the same Gracel Display Inc. (KR) 2009-05-06 EP disclosed
US-20070087222-A1 Organic electroluminescence device LG DISPLAY CO., LTD. (KR) 2007-04-19 US disclosed
US-20070087222-A1 Organic electroluminescence device LG DISPLAY CO., LTD. (KR) 2007-04-19 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090145483-A1 Novel electroluminescent compounds and organic electroluminescent device suing the same LEF1, ODC1, AOC2 PTGES 2987/4885ALOX5 682/4885TP53 4617/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.