Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 4/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | ALOX5 | P09917 | 4/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.40 |
| ▸ | AR | P10275 | 1/20 | 0.40 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.40 |
| ▸ | GABRA1 | P14867 | 3/20 | 0.40 |
| ▸ | GABRB2 | P47870 | 3/20 | 0.40 |
| ▸ | XDH | P47989 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | MAOA | P21397 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
| ▸ | PPARA | Q07869 | 2/20 | 0.38 |
| ▸ | PPARG | P37231 | 2/20 | 0.37 |
| ▸ | PPARD | Q03181 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12349787 | 0.89 | PTGS1 (0.60) | PTGS1MEN1KMT2ANPC1RAB9A | |
| SCHEMBL24472931 | 0.79 | POLB (0.52) | MEN1KMT2AALOX5ALDH1A1GABRA1 | |
| SCHEMBL12349867 | 0.76 | MGLL (0.47) | PTGS1MEN1KMT2ANPC1RAB9A | |
| SCHEMBL24472923 | 0.75 | POLB (0.49) | MEN1KMT2AALOX5ALDH1A1GABRA1 | |
| SCHEMBL13577775 | 0.74 | MAPT (0.50) | PTGS1MEN1KMT2AALOX5ALDH1A1 | |
| SCHEMBL31518918 | 0.74 | PTGS1 (0.67) | PTGS1MEN1KMT2ANPC1RAB9A | |
| SCHEMBL12349829 | 0.74 | L3MBTL1 (0.44) | KMT2ANPC1RAB9AALDH1A1L3MBTL1 | |
| SCHEMBL12446626 | 0.73 | SMN1; SMN2 (0.40) | MEN1KMT2AALDH1A1CYP3A4TDP1 | |
| SCHEMBL13567315 | 0.73 | LMNA (0.39) | PTGS1KMT2AALDH1A1L3MBTL1KDM4E | |
| SCHEMBL17350739 | 0.73 | KDM4E (0.43) | MEN1KMT2AALDH1A1L3MBTL1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090276042-A1 | Biological Polysiloxanes | VISION CRC LIMITED (AU) | 2009-11-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090276042-A1 | Biological Polysiloxanes | PBK, B2M, CD79B | PTGS1 2635/4885MEN1 782/4885KMT2A 1152/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.