Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 5/20 | 0.42 |
| ▸ | MAPK8 | P45983 | 3/20 | 0.41 |
| ▸ | CDC7 | O00311 | 1/20 | 0.39 |
| ▸ | CHUK | O15111 | 2/20 | 0.38 |
| ▸ | INSR | P06213 | 2/20 | 0.38 |
| ▸ | CAMKK2 | Q96RR4 | 2/20 | 0.38 |
| ▸ | ACHE | P22303 | 1/20 | 0.38 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.37 |
| ▸ | KCNMA1 | Q12791 | 2/20 | 0.37 |
| ▸ | FLT3 | P36888 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | EGFR | P00533 | 1/20 | 0.36 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.36 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12509464 | 0.90 | MAPK8 (0.43) | BRD4MAPK8CDC7CHUKINSR | |
| SCHEMBL2198247 | 0.86 | BRD4 (0.46) | BRD4CDC7KCNMA1ALDH1A1KDM4E | |
| SCHEMBL2195955 | 0.86 | CDK9 (0.42) | BRD4MAPK8CDC7CHUKINSR | |
| SCHEMBL12509581 | 0.85 | BRD4 (0.38) | BRD4MAPK8CDC7CHUKINSR | |
| SCHEMBL2196927 | 0.85 | CDC7 (0.54) | BRD4MAPK8CDC7CHUKINSR | |
| SCHEMBL13630194 | 0.83 | BRD4 (0.44) | BRD4MAPK8CDC7ACHEHPGD | |
| SCHEMBL2199022 | 0.81 | BRD4 (0.38) | BRD4MAPK8CDC7CHUKINSR | |
| SCHEMBL2197115 | 0.80 | ADORA3 (0.44) | BRD4CDC7HPGDALDH1A1KDM4E | |
| SCHEMBL13630645 | 0.80 | BRD4 (0.52) | BRD4MAPK8CDC7CHUKINSR | |
| SCHEMBL12509733 | 0.80 | BRD4 (0.39) | BRD4MAPK8KCNMA1ALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2116530-A1 | NOVEL PYRROLE DERIVATIVE HAVING UREIDE GROUP AND AMINOCARBONYL GROUP AS SUBSTITUENTS | Santen Pharmaceutical Co., Ltd (JP) | 2009-11-11 | — | — | EP | disclosed |