Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12652744 | 0.80 | HTT (0.31) | HTT | |
| SCHEMBL14986201 | 0.78 | — | — | |
| SCHEMBL10754465 | 0.74 | MEN1 (0.30) | MEN1MAPTHTTKMT2A | |
| SCHEMBL18491201 | 0.69 | MEN1 (0.36) | MEN1HTTKMT2A | |
| SCHEMBL188694 | 0.69 | MEN1 (0.41) | MEN1MAPTHTTKMT2A | |
| SCHEMBL14108617 | 0.67 | MEN1 (0.37) | MEN1MAPTHTTKMT2A | |
| SCHEMBL12599611 | 0.65 | — | — | |
| SCHEMBL7453267 | 0.64 | — | — | |
| SCHEMBL20503385 | 0.64 | HEXA (0.47) | MEN1KMT2A | |
| SCHEMBL5336235 | 0.64 | LMNA (0.32) | HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10316014-B2 | Facile and selective perfluoro-and polyfluoroarylation of meldrums acid | THE BOARD OF REGENTS FOR OKLAHOMA STATE UNIVERSITY (US) | 2019-06-11 | — | — | US | disclosed |
| US-20090274650-A1 | INHIBITORS OF ASPARTYL PROTEASE | VERTEX PHARMACEUTICALS INCORPORATED | 2009-11-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10316014-B2 | Facile and selective perfluoro-and polyfluoroarylation of meldrums acid | FXR2, NR1H4, FXR1 | MEN1 487/4885MAPT 3594/4885HTT 2244/4885 |
| US-20090274650-A1 | INHIBITORS OF ASPARTYL PROTEASE | SPINT2, DNPEP, PRSS1 | MEN1 4418/4885MAPT 1868/4885HTT 1847/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.