Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | POLB | P06746 | 3/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.40 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.40 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12361787 | 1.00 | ALDH1A1 (0.41) | ALDH1A1POLBGAAL3MBTL1KMT2A | |
| SCHEMBL13434260 | 1.00 | ALDH1A1 (0.41) | ALDH1A1POLBGAAL3MBTL1KMT2A | |
| SCHEMBL13631280 | 1.00 | ALDH1A1 (0.41) | ALDH1A1POLBGAAL3MBTL1KMT2A | |
| SCHEMBL12353628 | 0.91 | POLB (0.40) | ALDH1A1POLBL3MBTL1KMT2AOPRK1 | |
| SCHEMBL2820558 | 0.88 | SIGMAR1 (0.46) | POLBSIGMAR1KDM4EEPHX2 | |
| SCHEMBL2817309 | 0.88 | SIGMAR1 (0.46) | POLBSIGMAR1KDM4EEPHX2 | |
| SCHEMBL7602474 | 0.83 | HPGD (0.44) | ALDH1A1GAAL3MBTL1KMT2ASIGMAR1 | |
| SCHEMBL13434257 | 0.83 | L3MBTL1 (0.41) | ALDH1A1L3MBTL1KMT2ASIGMAR1OPRM1 | |
| SCHEMBL13434256 | 0.83 | L3MBTL1 (0.41) | ALDH1A1L3MBTL1KMT2ASIGMAR1OPRM1 | |
| SCHEMBL13631102 | 0.83 | L3MBTL1 (0.41) | ALDH1A1L3MBTL1KMT2ASIGMAR1OPRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2119702-A1 | AMIDE DERIVATIVE | Dainippon Sumitomo Pharma Co., Ltd. (JP) | 2009-11-18 | — | — | EP | disclosed |