Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM4 | Q14833 | 1/20 | 0.46 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.43 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.43 |
| ▸ | TNIK | Q9UKE5 | 3/20 | 0.42 |
| ▸ | SMARCA2 | P51531 | 1/20 | 0.41 |
| ▸ | SMARCA4 | P51532 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | TDO2 | P48775 | 1/20 | 0.37 |
| ▸ | UHRF1 | Q96T88 | 1/20 | 0.37 |
| ▸ | SORT1 | Q99523 | 3/20 | 0.37 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.37 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.37 |
| ▸ | GRM5 | P41594 | 1/20 | 0.36 |
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.36 |
| ▸ | XDH | P47989 | 1/20 | 0.36 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13632517 | 0.81 | GRM4 (0.46) | GRM4TNIKSMARCA2SMARCA4KDM4E | |
| SCHEMBL23999529 | 0.73 | RAD52 (0.57) | HDAC3HDAC1HDAC2HDAC6SMARCA2 | |
| SCHEMBL30180617 | 0.73 | RAD52 (0.57) | HDAC3HDAC1HDAC2HDAC6SMARCA2 | |
| SCHEMBL14300476 | 0.72 | TNIK (0.43) | GRM4TNIKKDM4EMAPTDYRK1A | |
| SCHEMBL31494286 | 0.72 | NPSR1 (0.53) | HDAC3HDAC1HDAC2HDAC6SMARCA2 | |
| SCHEMBL7659797 | 0.72 | NPSR1 (0.53) | HDAC3HDAC1HDAC2HDAC6SMARCA2 | |
| SCHEMBL23999556 | 0.71 | HDAC3 (0.43) | HDAC3HDAC1HDAC2HDAC6SMARCA2 | |
| SCHEMBL30210264 | 0.71 | HDAC3 (0.43) | HDAC3HDAC1HDAC2HDAC6SMARCA2 | |
| SCHEMBL2486834 | 0.71 | GRM4 (0.52) | GRM4TNIKKDM4EMAPTNPC1 | |
| SCHEMBL24003836 | 0.71 | NPC1 (0.56) | HDAC3HDAC1HDAC2HDAC6SMARCA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7622486-B2 | Pyridine compounds, process for their preparation and compositions containing them | REDDY US THERAPEUTICS, INC. (US) | 2009-11-24 | — | — | US | disclosed |