Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TNIK | Q9UKE5 | 1/20 | 0.43 |
| ▸ | APP | P05067 | 1/20 | 0.42 |
| ▸ | AURKA | O14965 | 6/20 | 0.42 |
| ▸ | RPS6KA6 | Q9UK32 | 1/20 | 0.42 |
| ▸ | RPS6KA3 | P51812 | 3/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.41 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.41 |
| ▸ | TNK2 | Q07912 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | SYK | P43405 | 2/20 | 0.40 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.38 |
| ▸ | PIM1 | P11309 | 1/20 | 0.38 |
| ▸ | CDK2 | P24941 | 1/20 | 0.38 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.38 |
| ▸ | GSK3B | P49841 | 1/20 | 0.38 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.38 |
| ▸ | HIPK2 | Q9H2X6 | 1/20 | 0.38 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.38 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14294394 | 0.90 | TNIK (0.41) | TNIKAPPAURKARPS6KA6RPS6KA3 | |
| SCHEMBL14293828 | 0.85 | RAB9A (0.44) | RPS6KA6TNK2SYKRAB9A | |
| SCHEMBL14293956 | 0.82 | RAB9A (0.53) | RPS6KA6MAPTRAB9A | |
| SCHEMBL14294396 | 0.80 | APP (0.56) | TNIKAPPMAPT | |
| SCHEMBL14300020 | 0.80 | TXN (0.54) | TNIKAPPGRM4KDM4EMAPT | |
| SCHEMBL14300477 | 0.79 | GALR1 (0.49) | RPS6KA6RPS6KA3TNK2CDK2 | |
| SCHEMBL655309 | 0.76 | SYK (0.70) | AURKARPS6KA3SYKMAP4K4CDK2 | |
| SCHEMBL13578882 | 0.74 | EGFR (0.42) | TNIKAURKAGRM4KDM4EMAPT | |
| SCHEMBL13632608 | 0.72 | GRM4 (0.46) | TNIKGRM4KDM4EMAPTDYRK1A | |
| SCHEMBL14293983 | 0.70 | RAB9A (0.53) | APPRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7335656-B2 | Stent with a disposed traiazine compound such as 6-(3-Chloro-4-methoxy-phenoxy)-N-cycloheptyl-N'-methyl-N'-(1-methyl-piperidin-4-yl)-[1,3,5]triazine-2,4-diamine for inhibiting smooth muscle proliferation; restenosis and atherosclerosis | REDDY US THERAPEUTICS, INC. (US) | 2008-02-26 | — | — | US | disclosed |
| US-7332490-B2 | Methods and compositions of novel triazine compounds | REDDY US THERAPEUTICS, INC. (US) | 2008-02-19 | — | — | US | disclosed |