Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 8/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.40 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.40 |
| ▸ | LDHA | P00338 | 1/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | FOS | P01100 | 1/20 | 0.36 |
| ▸ | TTR | P02766 | 1/20 | 0.36 |
| ▸ | JUN | P05412 | 1/20 | 0.36 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.36 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.36 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13623724 | 0.83 | SIGMAR1 (0.43) | SIGMAR1ALOX15ALOX12LDHASLC6A4 | |
| SCHEMBL13067270 | 0.81 | SLC6A4 (0.53) | ALOX15ALOX12SLC6A4 | |
| SCHEMBL13623709 | 0.77 | ADRA1D (0.48) | ALOX15ALOX12LDHACA2 | |
| SCHEMBL13623743 | 0.76 | SIGMAR1 (0.36) | SIGMAR1ALOX15ALOX12LDHASLC6A4 | |
| Hydrochloric Acid SCHEMBL4365244 | 0.76 | ADRA1D (0.47) | SIGMAR1ALOX15ALOX12LDHACA2 | |
| SCHEMBL14040035 | 0.74 | LDHA (0.36) | SIGMAR1ALOX15ALOX12LDHASLC6A4 | |
| SCHEMBL14534149 | 0.74 | SLC6A4 (0.61) | LDHASLC6A4 | |
| SCHEMBL14039756 | 0.73 | LDHA (0.38) | SIGMAR1ALOX15ALOX12LDHAFOS | |
| SCHEMBL16930335 | 0.69 | SIGMAR1 (0.56) | SIGMAR1ALOX15ALOX12LDHAFOS | |
| SCHEMBL10842397 | 0.69 | LDHA (0.56) | SIGMAR1ALOX15ALOX12LDHASLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7619116-B2 | Intermediates for the synthesis of (R)-tamsulosin and of its pharmaceutically acceptable salts and process for their preparation | Products Chimiques Auxiliaires Et de Synthese (FR) | 2009-11-17 | — | — | US | disclosed |
| EP-1697316-B1 | NOVEL INTERMEDIATES FOR THE SYNTHESIS OF (R)-TAMSULOSIN AND OF ITS PHARMACEUTICALLY ACCEPTABLE SALTS AND PROCESS FOR THEIR PREPARATION | PROD CHIM AUXILIAIRES ET DE SY (FR) | 2008-10-08 | — | — | EP | disclosed |