SCHEMBL13633270

SCHEMBL13633270

C=CC(=O)OCCOc1ccccc1N/N=C(\C(C)=O)C(=O)Nc1ccccc1OCC

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GAA P10253 1/20 0.43
THRB P10828 1/20 0.41
LMNA P02545 2/20 0.41
MCL1 Q07820 1/20 0.41
MAPT P10636 4/20 0.41
ALDH1A1 P00352 2/20 0.41
MAPK1 P28482 1/20 0.41
KMT2A Q03164 6/20 0.40
EGFR P00533 1/20 0.40
TSHR P16473 1/20 0.40
KDM4E B2RXH2 3/20 0.40
CYP2C19 P33261 1/20 0.40
L3MBTL1 Q9Y468 1/20 0.40
MEN1 O00255 3/20 0.39
KCNH2 Q12809 1/20 0.39
SMN1; SMN2 Q16637 2/20 0.39
MITF O75030 1/20 0.39
GLA P06280 1/20 0.39
HTT P42858 1/20 0.39
POLB P06746 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12998511 0.93 MAPT (0.48) THRBLMNAMAPTALDH1A1MAPK1
SCHEMBL12998590 0.93 MAPT (0.48) THRBLMNAMAPTALDH1A1MAPK1
SCHEMBL13136362 0.86 MAPT (0.44) THRBLMNAMAPTALDH1A1MAPK1
SCHEMBL12998507 0.84 GAA (0.47) GAALMNAMAPTALDH1A1MAPK1
SCHEMBL12998503 0.81 MAPT (0.46) GAAMAPTALDH1A1MAPK1KMT2A
SCHEMBL14625933 0.80 THRB (0.49) GAATHRBLMNAMCL1MAPT
SCHEMBL13707258 0.79 THRB (0.40) THRBMAPTALDH1A1MAPK1KMT2A
SCHEMBL13924951 0.78 MAPT (0.47) LMNAMAPTALDH1A1MAPK1KMT2A
SCHEMBL12998586 0.78 MAPT (0.47) LMNAMAPTALDH1A1MAPK1KMT2A
SCHEMBL13948380 0.78 MAPT (0.47) LMNAMAPTALDH1A1MAPK1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1904592-B1 PHENYLAZO-ACETOACETANILIDE DERIVATIVES WITH A POLYMER! ZABLE FUNCTIONAL GROUP AND RELATED COMPOUNDS AS MONOMERS FOR PREPARING POLYMERIC PIGMENT DISPERSANTS FOR INKJET INKS AGFA GRAPHICS NV (BE) 2009-11-25 EP disclosed