Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | CASP6 | P55212 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.34 |
| ▸ | MEN1 | O00255 | 5/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12998590 | 0.90 | MAPT (0.48) | MAPTALDH1A1MAPK1POLBCASP6 | |
| SCHEMBL12998511 | 0.90 | MAPT (0.48) | MAPTALDH1A1MAPK1POLBCASP6 | |
| SCHEMBL764920 | 0.87 | MAPT (0.49) | MAPTALDH1A1MAPK1POLBCASP6 | |
| SCHEMBL13135316 | 0.86 | MAPT (0.40) | MAPTALDH1A1MAPK1TDP1THRB | |
| SCHEMBL12998507 | 0.86 | GAA (0.47) | MAPTALDH1A1MAPK1POLBSMN1; SMN2 | |
| SCHEMBL13633270 | 0.86 | GAA (0.43) | MAPTALDH1A1MAPK1POLBTHRB | |
| SCHEMBL12329801 | 0.77 | ALDH1A1 (0.53) | MAPTALDH1A1MAPK1POLBCASP6 | |
| SCHEMBL13707258 | 0.77 | THRB (0.40) | MAPTALDH1A1MAPK1POLBCASP6 | |
| SCHEMBL12998503 | 0.77 | MAPT (0.46) | MAPTALDH1A1MAPK1POLBTDP1 | |
| SCHEMBL765365 | 0.75 | MAPT (0.55) | MAPTALDH1A1MAPK1POLBCASP6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7812113-B2 | Phenylazo-acetoacetanilide derivatives with a polymerizable functional group and related compounds as monomers for preparing polymeric pigment dispersants for inkjet inks | AGFA GRAPHICS NV (BE) | 2010-10-12 | — | — | US | disclosed |