Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 4/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | NLRP1 | Q9C000 | 1/20 | 0.41 |
| ▸ | BRD4 | O60885 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | EGFR | P00533 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9245556 | 0.83 | THRB (0.49) | THRBLMNASMN1; SMN2KMT2ATDP1 | |
| SCHEMBL12998590 | 0.81 | MAPT (0.48) | THRBLMNASMN1; SMN2KMT2ATDP1 | |
| SCHEMBL12998511 | 0.81 | MAPT (0.48) | THRBLMNASMN1; SMN2KMT2ATDP1 | |
| SCHEMBL13633270 | 0.80 | GAA (0.43) | THRBLMNASMN1; SMN2KMT2AALDH1A1 | |
| SCHEMBL14625093 | 0.78 | THRB (0.57) | THRBLMNASMN1; SMN2KMT2ATDP1 | |
| SCHEMBL15255640 | 0.75 | LMNA (0.67) | THRBLMNASMN1; SMN2KMT2AALDH1A1 | |
| SCHEMBL13696936 | 0.75 | POLB (0.60) | LMNASMN1; SMN2KMT2ATDP1ALDH1A1 | |
| SCHEMBL13707258 | 0.74 | THRB (0.40) | THRBSMN1; SMN2KMT2ATDP1ALDH1A1 | |
| SCHEMBL1828411 | 0.74 | THRB (0.62) | THRBLMNASMN1; SMN2TDP1ALDH1A1 | |
| SCHEMBL28121765 | 0.74 | THRB (0.62) | THRBLMNASMN1; SMN2TDP1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007006682-A1 | PHENYLAZO-ACETOACETANILIDE DERIVATIVES WITH A POLYMER! ZABLE FUNCTIONAL GROUP AND RELATED COMPOUNDS AS MONOMERS FOR PREPARING POLYMERIC PIGMENT DISPERSANTS FOR INKJET INKS | AGFA GRAPHICS NV (BE) | 2007-01-18 | — | — | WO | disclosed |