Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP3K5 | Q99683 | 5/20 | 0.40 |
| ▸ | METTL3 | Q86U44 | 2/20 | 0.39 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.35 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.35 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.35 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.35 |
| ▸ | PIK3C3 | Q8NEB9 | 1/20 | 0.35 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13633518 | 0.82 | KDM4E (0.46) | MAP3K5METTL3PIK3CAPIK3CDPIK3CB | |
| SCHEMBL1302968 | 0.81 | MAP3K5 (0.60) | MAP3K5PIK3CAPIK3CDPIK3CBPIK3CG | |
| SCHEMBL20798098 | 0.79 | RAB9A (0.49) | MAP3K5HDAC4L3MBTL1HDAC1KDM4E | |
| SCHEMBL13633508 | 0.76 | METTL3 (0.42) | METTL3 | |
| SCHEMBL5935848 | 0.75 | HRH4 (0.41) | MAP3K5PIK3CAPIK3CDPIK3CBPIK3CG | |
| SCHEMBL13633553 | 0.74 | KMT2A (0.50) | METTL3KDM4ENPC1ALDH1A1RAB9A | |
| SCHEMBL25349894 | 0.74 | RXFP1 (0.37) | MAP3K5L3MBTL1PIK3CAKDM4ESMN1; SMN2 | |
| SCHEMBL3710368 | 0.74 | PIK3CA (0.42) | MAP3K5PIK3CAPIK3CDPIK3CBPIK3CG | |
| SCHEMBL16439354 | 0.74 | KDM4E (0.36) | METTL3HDAC4L3MBTL1HDAC1KDM4E | |
| SCHEMBL3705966 | 0.74 | PIK3CD (0.45) | PIK3CDPIK3CGKDM4ENPC1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015014283-A1 | PROTEIN TYROSINE KINASE INHIBITOR AND APPLICATION THEREOF | 南京圣和药业股份有限公司 (CN) | 2015-02-05 | — | — | WO | disclosed |
| US-20090275577-A1 | IMIDAZOPYRIDINE AND IMIDAZOPYRIMIDINE DERIVATIVES AS ANTIBACTERIAL AGENTS | PFIZER INC | 2009-11-05 | — | — | US | disclosed |
| US-7563788-B2 | Substituted Imidazo[1,2-a]pyridines as Antibacterial Agents | PFIZER INC. (US) | 2009-07-21 | — | — | US | disclosed |
| US-20070191394-A1 | Antibacterial agents | WARNER-LAMBERT COMPANY LLC | 2007-08-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070191394-A1 | Antibacterial agents | MRPL21, RPN2, FBL | MAP3K5 3024/4885METTL3 4671/4885HDAC4 1950/4885 |
| US-20090275577-A1 | IMIDAZOPYRIDINE AND IMIDAZOPYRIMIDINE DERIVATIVES AS ANTIBACTERIAL AGENTS | DPYD, TYMP, ITPA | MAP3K5 1536/4885METTL3 4732/4885HDAC4 602/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.