Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TTR | P02766 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 4/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.38 |
| ▸ | ACHE | P22303 | 3/20 | 0.38 |
| ▸ | THRB | P10828 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 4/20 | 0.33 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | TP53 | P04637 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 2/20 | 0.32 |
| ▸ | RAB9A | P51151 | 2/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | HSPD1 | P10809 | 1/20 | 0.32 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.32 |
| ▸ | HSPE1 | P61604 | 1/20 | 0.32 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4197112 | 1.00 | TTR (0.40) | TTRPOLBKMT2AACHETHRB | |
| SCHEMBL13633604 | 0.94 | TTR (0.40) | TTRPOLBKMT2AACHETHRB | |
| SCHEMBL4187766 | 0.94 | TTR (0.40) | TTRPOLBKMT2AACHETHRB | |
| SCHEMBL4192297 | 0.89 | GAA (0.37) | TTRPOLBKMT2AACHEMAPT | |
| Bromide SCHEMBL4190244 | 0.88 | GAA (0.36) | TTRPOLBKMT2AACHEMAPT | |
| SCHEMBL4178439 | 0.87 | MAPT (0.34) | TTRPOLBKMT2AACHETHRB | |
| SCHEMBL13633675 | 0.86 | ACHE (0.33) | POLBKMT2AACHEMAPTTP53 | |
| SCHEMBL12907529 | 0.85 | TTR (0.38) | TTRPOLBKMT2AACHEMAPT | |
| Bromide SCHEMBL8908965 | 0.84 | TTR (0.37) | TTRPOLBKMT2AACHEMAPT | |
| SCHEMBL4192623 | 0.83 | ACHE (0.34) | TTRPOLBKMT2AACHETHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7611909-B1 | Acridinium compound for use in the concurrent detection of target analytes in immunoassays or nucleic acid assays | SIEMENS HEALTHCARE DIAGNOSTICS INC. (US) | 2009-11-03 | — | — | US | disclosed |