SCHEMBL13633675

SCHEMBL13633675

Cc1cc(C(=O)ON2C(=O)CCC2=O)cc(C)c1OC(=O)c1c2ccccc2[n+](C)c2ccc(/C=C/c3ccc(O)cc3)cc12

nearest known ligand 0.33

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
ACHE P22303 3/20 0.33
POLB P06746 2/20 0.33
KMT2A Q03164 2/20 0.33
TP53 P04637 1/20 0.31
MAPT P10636 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4187500 0.95 POLB (0.31) ACHEPOLBKMT2ATP53MAPT
SCHEMBL4194167 0.90 KDM4E (0.32) ACHEPOLBTP53MAPTSMN1; SMN2
SCHEMBL31163697 0.88 ACHE (0.32) ACHEKMT2ATP53MAPT
SCHEMBL641602 0.88 ACHE (0.32) ACHEKMT2ATP53MAPT
SCHEMBL13633608 0.86 TTR (0.40) ACHEPOLBKMT2ATP53MAPT
SCHEMBL4197112 0.86 TTR (0.40) ACHEPOLBKMT2ATP53MAPT
SCHEMBL4187542 0.82
SCHEMBL13633605 0.81 POLB (0.31) ACHEPOLBKMT2A
SCHEMBL29373064 0.81 TERT (0.36) SMN1; SMN2
SCHEMBL8910403 0.81 TERT (0.36) SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7611909-B1 Acridinium compound for use in the concurrent detection of target analytes in immunoassays or nucleic acid assays SIEMENS HEALTHCARE DIAGNOSTICS INC. (US) 2009-11-03 US disclosed