Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 7/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | DPP4 | P27487 | 1/20 | 0.36 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.36 |
| ▸ | PDE4A | P27815 | 1/20 | 0.36 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.36 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.36 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | OGA | O60502 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.35 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10278217 | 0.91 | HRH3 (0.48) | HRH3L3MBTL1RAB9ANPC1ALDH1A1 | |
| SCHEMBL3559247 | 0.91 | HRH3 (0.55) | HRH3L3MBTL1RAB9ANPC1SMN1; SMN2 | |
| SCHEMBL13634365 | 0.84 | HRH3 (0.47) | HRH3L3MBTL1RAB9ANPC1ALDH1A1 | |
| SCHEMBL13634230 | 0.81 | HRH3 (0.55) | HRH3L3MBTL1RAB9ANPC1SMN1; SMN2 | |
| SCHEMBL13634265 | 0.81 | HRH3 (0.42) | HRH3RAB9ANPC1ALDH1A1MAPT | |
| SCHEMBL3555940 | 0.80 | HRH3 (0.44) | HRH3L3MBTL1RAB9ANPC1ALDH1A1 | |
| SCHEMBL13162579 | 0.79 | HRH3 (0.47) | HRH3RAB9ANPC1ALDH1A1SMN1; SMN2 | |
| SCHEMBL13634311 | 0.79 | HRH3 (0.47) | HRH3RAB9ANPC1ALDH1A1SMN1; SMN2 | |
| SCHEMBL13634364 | 0.78 | HRH3 (0.46) | HRH3L3MBTL1RAB9ANPC1ALDH1A1 | |
| SCHEMBL29225087 | 0.78 | HRH3 (0.46) | HRH3L3MBTL1RAB9ANPC1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8304547-B2 | Azolecarboxamide compound or salt thereof | ASTELLAS PHARMA INC. (JP) | 2012-11-06 | — | — | US | disclosed |