Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | DPP4 | P27487 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.39 |
| ▸ | NPC1 | O15118 | 5/20 | 0.39 |
| ▸ | RAB9A | P51151 | 5/20 | 0.39 |
| ▸ | F2RL3 | Q96RI0 | 1/20 | 0.37 |
| ▸ | OGA | O60502 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29225087 | 1.00 | HRH3 (0.46) | HRH3L3MBTL1DPP4SMN1; SMN2NPC1 | |
| SCHEMBL13270746 | 0.86 | L3MBTL1 (0.42) | HRH3L3MBTL1DPP4SMN1; SMN2NPC1 | |
| SCHEMBL3555940 | 0.82 | HRH3 (0.44) | HRH3L3MBTL1DPP4SMN1; SMN2NPC1 | |
| SCHEMBL13634185 | 0.78 | HRH3 (0.50) | HRH3L3MBTL1DPP4SMN1; SMN2NPC1 | |
| SCHEMBL10136842 | 0.78 | HRH3 (0.49) | HRH3L3MBTL1DPP4SMN1; SMN2NPC1 | |
| SCHEMBL3435674 | 0.77 | PTGER1 (0.46) | HRH3SMN1; SMN2OGAALDH1A1 | |
| SCHEMBL3435745 | 0.77 | PTGER1 (0.46) | HRH3SMN1; SMN2OGAALDH1A1 | |
| SCHEMBL458365 | 0.76 | HRH3 (0.48) | HRH3L3MBTL1DPP4SMN1; SMN2NPC1 | |
| SCHEMBL10136897 | 0.76 | L3MBTL1 (0.49) | HRH3L3MBTL1DPP4SMN1; SMN2NPC1 | |
| SCHEMBL5724256 | 0.76 | HRH3 (0.51) | HRH3L3MBTL1SMN1; SMN2NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8304547-B2 | Azolecarboxamide compound or salt thereof | ASTELLAS PHARMA INC. (JP) | 2012-11-06 | — | — | US | disclosed |