Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC12A5 | Q9H2X9 | 4/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | NOS1 | P29475 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13634190 | 0.83 | KDM4E (0.38) | SLC12A5CYP2D6MEN1KMT2ALMNA | |
| SCHEMBL13162587 | 0.81 | L3MBTL1 (0.41) | MEN1KMT2AKDM4EALDH1A1CYP1A2 | |
| SCHEMBL13270657 | 0.77 | MEN1 (0.33) | MEN1KMT2AHSD17B10ALDH1A1MAPT | |
| SCHEMBL13162285 | 0.77 | MAOA (0.40) | MEN1KMT2ALMNAHSD17B10GAA | |
| SCHEMBL13425206 | 0.75 | KDM4E (0.40) | SLC12A5CYP2D6MEN1KMT2ALMNA | |
| SCHEMBL9955496 | 0.75 | SLC12A5 (0.49) | SLC12A5CYP2D6MEN1KMT2ALMNA | |
| SCHEMBL232983 | 0.74 | SMN1; SMN2 (0.40) | SLC12A5CYP2D6MEN1KMT2ALMNA | |
| SCHEMBL3506347 | 0.74 | MAPK1 (0.42) | SLC12A5CYP2D6MEN1KMT2ALMNA | |
| SCHEMBL23723506 | 0.73 | SLC12A5 (0.48) | SLC12A5CYP2D6MEN1KMT2ALMNA | |
| SCHEMBL23723568 | 0.73 | SLC12A5 (0.48) | SLC12A5CYP2D6MEN1KMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8304547-B2 | Azolecarboxamide compound or salt thereof | ASTELLAS PHARMA INC. (JP) | 2012-11-06 | — | — | US | disclosed |