Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | SLC12A5 | Q9H2X9 | 2/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.37 |
| ▸ | NOS1 | P29475 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 3/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13634191 | 0.83 | SLC12A5 (0.40) | KDM4ESLC12A5CYP2D6SMN1; SMN2NOS1 | |
| SCHEMBL13270554 | 0.81 | L3MBTL1 (0.41) | KDM4ESMN1; SMN2ALDH1A1MEN1KMT2A | |
| SCHEMBL13162299 | 0.77 | MAOA (0.40) | KDM4ESMN1; SMN2LMNAALDH1A1RAB9A | |
| Hydrochloric Acid SCHEMBL27945128 | 0.76 | SLC12A5 (0.41) | KDM4ESLC12A5CYP2D6SMN1; SMN2NOS1 | |
| SCHEMBL13425206 | 0.75 | KDM4E (0.40) | KDM4ESLC12A5CYP2D6SMN1; SMN2LMNA | |
| SCHEMBL232983 | 0.74 | SMN1; SMN2 (0.40) | KDM4ESLC12A5CYP2D6SMN1; SMN2NOS1 | |
| SCHEMBL3506347 | 0.74 | MAPK1 (0.42) | KDM4ESLC12A5CYP2D6SMN1; SMN2NOS1 | |
| SCHEMBL9955496 | 0.72 | SLC12A5 (0.49) | KDM4ESLC12A5CYP2D6SMN1; SMN2NOS1 | |
| SCHEMBL13634342 | 0.72 | NOS1 (0.38) | KDM4ESLC12A5CYP2D6SMN1; SMN2NOS1 | |
| SCHEMBL13653784 | 0.72 | NPC1 (0.54) | KDM4ESLC12A5CYP2D6SMN1; SMN2NOS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8304547-B2 | Azolecarboxamide compound or salt thereof | ASTELLAS PHARMA INC. (JP) | 2012-11-06 | — | — | US | disclosed |