Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 6/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | PKM | P14618 | 1/20 | 0.48 |
| ▸ | GLS | O94925 | 2/20 | 0.47 |
| ▸ | RECQL | P46063 | 1/20 | 0.47 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.47 |
| ▸ | USP2 | O75604 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | FAAH | O00519 | 1/20 | 0.44 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3561605 | 0.91 | GPR119 (0.46) | GPR119HPGDKDM4EPKMGLS | |
| SCHEMBL31209154 | 0.91 | GPR119 (0.46) | GPR119HPGDKDM4EPKMGLS | |
| SCHEMBL34474175 | 0.91 | GPR119 (0.46) | GPR119HPGDKDM4EPKMGLS | |
| SCHEMBL1329227 | 0.87 | GPR119 (0.48) | GPR119HPGDKDM4EPKMGLS | |
| SCHEMBL28062966 | 0.83 | HPGD (0.50) | GPR119HPGDKDM4EPKMGLS | |
| SCHEMBL6608848 | 0.83 | HPGD (0.53) | GPR119HPGDKDM4EPKMGLS | |
| SCHEMBL1401260 | 0.83 | HPGD (0.53) | GPR119HPGDKDM4EPKMRECQL | |
| SCHEMBL584378 | 0.83 | KDM4E (0.54) | GPR119HPGDKDM4EPKMGLS | |
| SCHEMBL844078 | 0.83 | HPGD (0.53) | GPR119HPGDKDM4EPKMGLS | |
| SCHEMBL30793939 | 0.82 | GLS (0.47) | GPR119HPGDGLSEPHX1NR1H2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12213970-B2 | Pyridinyl sulfonamide derivatives, pharmaceutical compositions and uses thereof | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2025-02-04 | — | — | US | disclosed |
| US-20240383873-A1 | PESTICIDALLY ACTIVE CYCLIC AMINE COMPOUNDS | SYNGENTA CROP PROTECTION AG (CH) | 2024-11-21 | — | — | US | disclosed |
| CN-112955214-B | Pyridylsulfonamide derivatives, pharmaceutical compositions and uses thereof | 勃林格殷格翰国际有限公司 | 2024-05-07 | — | — | CN | disclosed |
| CN-117642385-A | Pesticidally active cyclic amine compounds | 先正达农作物保护股份公司 | 2024-03-01 | — | — | CN | disclosed |
| EP-4323343-A2 | PYRIDINE DERIVATIVES AND THEIR USE AS PESTICIDE | Syngenta Crop Protection AG (CH) | 2024-02-21 | — | — | EP | disclosed |
| EP-3790871-B1 | FURIN INHIBITORS | GLAXOSMITHKLINE IP DEV LTD (GB) | 2024-01-24 | — | — | EP | disclosed |
| US-11773078-B2 | Furin inhibitors | GLAXOSMITHKLINE INTELLECTUAL PROPERTY DEVELOPMENT LIMITED (GB) | 2023-10-03 | — | — | US | disclosed |
| EP-3873599-B1 | PYRIDINYL SULFONAMIDE DERIVATIVES, PHARMACEUTICAL COMPOSITIONS AND USES THEREOF | BOEHRINGER INGELHEIM INT (DE) | 2023-09-27 | — | — | EP | disclosed |
| EP-3873599-B1 | PYRIDINYL SULFONAMIDE DERIVATIVES, PHARMACEUTICAL COMPOSITIONS AND USES THEREOF | BOEHRINGER INGELHEIM INT (DE) | 2023-09-27 | — | — | EP | disclosed |
| WO-2022219146-A2 | PESTICIDALLY ACTIVE CYCLIC AMINE COMPOUNDS | SYNGENTA CROP PROTECTION AG (CH) | 2022-10-20 | — | — | WO | disclosed |
| US-20220315556-A1 | FURIN INHIBITORS | GLAXOSMITHKLINE INTELLECTUAL PROPERTY DEVELOPMENT LIMITED (GB) | 2022-10-06 | — | — | US | disclosed |
| US-20210353608-A1 | PYRIDINYL SULFONAMIDE DERIVATIVES, PHARMACEUTICAL COMPOSITIONS AND USES THEREOF | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2021-11-18 | — | — | US | disclosed |
| US-20210353608-A1 | PYRIDINYL SULFONAMIDE DERIVATIVES, PHARMACEUTICAL COMPOSITIONS AND USES THEREOF | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2021-11-18 | — | — | US | disclosed |
| EP-3873599-A1 | PYRIDINYL SULFONAMIDE DERIVATIVES, PHARMACEUTICAL COMPOSITIONS AND USES THEREOF | Boehringer Ingelheim International GmbH (DE) | 2021-09-08 | — | — | EP | disclosed |
| CN-112955214-A | Pyridylsulfonamide derivatives, pharmaceutical compositions and uses thereof | 勃林格殷格翰国际有限公司 | 2021-06-11 | — | — | CN | disclosed |
| EP-3790871-A1 | FURIN INHIBITORS | GlaxoSmithKline Intellectual Property Development Limited (GB) | 2021-03-17 | — | — | EP | disclosed |
| WO-2019215341-A1 | FURIN INHIBITORS | GLAXOSMITHKLINE INTELLECTUAL PROPERTY DEVELOPMENT LIMITED (GB) | 2019-11-14 | — | — | WO | disclosed |
| US-20100197908-A1 | Pyridazine Derivatives with MCH Antagonistic Activity and Medicaments Comprising These Compounds | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2010-08-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210353608-A1 | PYRIDINYL SULFONAMIDE DERIVATIVES, PHARMACEUTICAL COMPOSITIONS AND USES THEREOF | ARSA, SULT1A1, SULT2A1 | GPR119 2058/4885HPGD 598/4885KDM4E 3461/4885 |
| US-20220315556-A1 | FURIN INHIBITORS | FURIN, TGFB1, PCSK7 | GPR119 2318/4885HPGD 779/4885KDM4E 4275/4885 |
| US-20100197908-A1 | Pyridazine Derivatives with MCH Antagonistic Activity and Medicaments Comprising These Compounds | MCHR1, MCHR2, MC5R | GPR119 8/4885HPGD 1286/4885KDM4E 1410/4885 |
| US-12213970-B2 | Pyridinyl sulfonamide derivatives, pharmaceutical compositions and uses thereof | ARSA, SULT1A1, SULT2A1 | GPR119 2058/4885HPGD 598/4885KDM4E 3461/4885 |
| US-20240383873-A1 | PESTICIDALLY ACTIVE CYCLIC AMINE COMPOUNDS | DDT, PNMT, ACHE | GPR119 1801/4885HPGD 2428/4885KDM4E 2430/4885 |
| US-11773078-B2 | Furin inhibitors | FURIN, TGFB1, PCSK7 | GPR119 2318/4885HPGD 779/4885KDM4E 4275/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.