Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLA2G4A | P47712 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | MMP1 | P03956 | 1/20 | 0.39 |
| ▸ | MMP2 | P08253 | 1/20 | 0.39 |
| ▸ | MMP9 | P14780 | 1/20 | 0.39 |
| ▸ | MMP13 | P45452 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | ACHE | P22303 | 1/20 | 0.36 |
| ▸ | DHODH | Q02127 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15888636 | 0.87 | L3MBTL1 (0.41) | PLA2G4AL3MBTL1ALDH1A1MMP1MMP2 | |
| SCHEMBL13162589 | 0.87 | L3MBTL1 (0.41) | PLA2G4AL3MBTL1ALDH1A1MMP1MMP2 | |
| SCHEMBL13634202 | 0.84 | MEN1 (0.38) | PLA2G4AL3MBTL1ALDH1A1MMP1MMP2 | |
| SCHEMBL3551333 | 0.83 | ALDH1A1 (0.41) | PLA2G4AL3MBTL1ALDH1A1MMP1MMP2 | |
| SCHEMBL13163971 | 0.82 | L3MBTL1 (0.38) | PLA2G4AL3MBTL1ALDH1A1MMP1MMP2 | |
| Hydrochloric Acid SCHEMBL2077470 | 0.82 | ALDH1A1 (0.40) | PLA2G4AL3MBTL1ALDH1A1MMP1MMP2 | |
| SCHEMBL13634355 | 0.80 | L3MBTL1 (0.36) | PLA2G4AL3MBTL1ALDH1A1MMP1MMP2 | |
| SCHEMBL13634203 | 0.80 | L3MBTL1 (0.36) | PLA2G4AL3MBTL1ALDH1A1MMP1MMP2 | |
| SCHEMBL13270554 | 0.79 | L3MBTL1 (0.41) | PLA2G4AL3MBTL1ALDH1A1MMP1MMP2 | |
| SCHEMBL13162587 | 0.79 | L3MBTL1 (0.41) | PLA2G4AL3MBTL1ALDH1A1MMP1MMP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8304547-B2 | Azolecarboxamide compound or salt thereof | ASTELLAS PHARMA INC. (JP) | 2012-11-06 | — | — | US | disclosed |