Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | PLA2G4A | P47712 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | MMP1 | P03956 | 1/20 | 0.35 |
| ▸ | MMP2 | P08253 | 1/20 | 0.35 |
| ▸ | MMP9 | P14780 | 1/20 | 0.35 |
| ▸ | MMP13 | P45452 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
| ▸ | RARA | P10276 | 1/20 | 0.33 |
| ▸ | RARB | P10826 | 1/20 | 0.33 |
| ▸ | RARG | P13631 | 1/20 | 0.33 |
| ▸ | ACHE | P22303 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3551333 | 0.86 | ALDH1A1 (0.41) | MEN1KMT2APLA2G4AL3MBTL1ALDH1A1 | |
| Hydrochloric Acid SCHEMBL2077470 | 0.84 | ALDH1A1 (0.40) | MEN1KMT2APLA2G4AL3MBTL1ALDH1A1 | |
| SCHEMBL13634208 | 0.84 | PLA2G4A (0.46) | MEN1KMT2APLA2G4AL3MBTL1ALDH1A1 | |
| SCHEMBL13634355 | 0.82 | L3MBTL1 (0.36) | MEN1KMT2APLA2G4AL3MBTL1ALDH1A1 | |
| SCHEMBL13634203 | 0.82 | L3MBTL1 (0.36) | MEN1KMT2APLA2G4AL3MBTL1ALDH1A1 | |
| SCHEMBL13162589 | 0.81 | L3MBTL1 (0.41) | MEN1KMT2APLA2G4AL3MBTL1ALDH1A1 | |
| SCHEMBL15888636 | 0.81 | L3MBTL1 (0.41) | PLA2G4AL3MBTL1ALDH1A1MMP1MMP2 | |
| SCHEMBL13634299 | 0.77 | MEN1 (0.41) | MEN1KMT2A | |
| SCHEMBL9911158 | 0.77 | MEN1 (0.33) | MEN1KMT2A | |
| SCHEMBL13162587 | 0.77 | L3MBTL1 (0.41) | MEN1KMT2APLA2G4AL3MBTL1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2206707-B1 | AZOLECARBOXAMIDE COMPOUND OR SALT THEREOF | ASTELLAS PHARMA INC (JP) | 2014-07-23 | — | — | EP | disclosed |
| US-8304547-B2 | Azolecarboxamide compound or salt thereof | ASTELLAS PHARMA INC. (JP) | 2012-11-06 | — | — | US | disclosed |
| US-8304547-B2 | Azolecarboxamide compound or salt thereof | ASTELLAS PHARMA INC. (JP) | 2012-11-06 | — | — | US | disclosed |