Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.47 |
| ▸ | BACE1 | P56817 | 4/20 | 0.42 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.42 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.42 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.42 |
| ▸ | FLT1 | P17948 | 1/20 | 0.42 |
| ▸ | FGFR3 | P22607 | 1/20 | 0.42 |
| ▸ | KDR | P35968 | 1/20 | 0.42 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.41 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.41 |
| ▸ | TUBB | P07437 | 1/20 | 0.41 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.41 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.41 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.41 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.41 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.41 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.41 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2769859 | 0.87 | SIRT6 (0.50) | SIRT6TDP1PTGS2BACE1PDGFRB | |
| SCHEMBL2769860 | 0.87 | SIRT6 (0.50) | SIRT6TDP1PTGS2BACE1PDGFRB | |
| SCHEMBL2772097 | 0.85 | SIRT6 (0.53) | SIRT6TDP1PDGFRBFGFR1PDGFRA | |
| SCHEMBL648496 | 0.84 | SIRT6 (0.55) | SIRT6TDP1PTGS2BACE1PDGFRB | |
| SCHEMBL27358645 | 0.82 | MEN1 (0.51) | SIRT6TDP1PDGFRBFGFR1PDGFRA | |
| SCHEMBL27344177 | 0.82 | MEN1 (0.51) | SIRT6TDP1PDGFRBFGFR1PDGFRA | |
| SCHEMBL1202192 | 0.81 | ALDH1A1 (0.41) | SIRT6TDP1PTGS2PDGFRBFGFR1 | |
| SCHEMBL1202190 | 0.81 | ALDH1A1 (0.41) | SIRT6TDP1PTGS2PDGFRBFGFR1 | |
| SCHEMBL11389602 | 0.79 | TDP1 (0.59) | SIRT6TDP1PTGS2BACE1MAPT | |
| SCHEMBL145815 | 0.77 | SIRT6 (0.57) | SIRT6TDP1PDGFRBFGFR1PDGFRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8304547-B2 | Azolecarboxamide compound or salt thereof | ASTELLAS PHARMA INC. (JP) | 2012-11-06 | — | — | US | disclosed |