SCHEMBL13634231

SCHEMBL13634231

CCCNC(=O)c1cc(CN2CCOCC2)c(C)cc1NC(=O)OC(C)(C)C

nearest known ligand 0.50

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
CNR2 P34972 14/20 0.50
CD274 Q9NZQ7 2/20 0.46
CNR1 P21554 6/20 0.44
MAPT P10636 1/20 0.40
ACHE P22303 1/20 0.39
BACE1 P56817 1/20 0.39
PDCD1 Q15116 1/20 0.39
KDM4E B2RXH2 1/20 0.39
GAA P10253 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13162811 0.92 KMT2A (0.48) CNR2CD274CNR1MAPT
SCHEMBL13634352 0.81 CCR2 (0.39) CNR2ACHEBACE1
SCHEMBL2771372 0.79 KMT2A (0.53) CNR2CD274PDCD1KDM4E
SCHEMBL13634358 0.79 CNR2 (0.47) CNR2CNR1MAPTKDM4E
SCHEMBL13634497 0.73 KMT2A (0.61) CNR2KDM4E
SCHEMBL26628833 0.73 MEN1 (0.58) CNR2CD274CNR1MAPTPDCD1
SCHEMBL29109429 0.73 MEN1 (0.47) CNR2CD274CNR1MAPTPDCD1
SCHEMBL13634354 0.73 CCR2 (0.45) ACHEBACE1GAA
SCHEMBL4975316 0.72 SMN1; SMN2 (0.52) CNR2CD274MAPT
SCHEMBL26628831 0.72 TSHR (0.52) CNR2CD274MAPTKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8304547-B2 Azolecarboxamide compound or salt thereof ASTELLAS PHARMA INC. (JP) 2012-11-06 US disclosed