Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR2 | P41597 | 3/20 | 0.39 |
| ▸ | DPP4 | P27487 | 2/20 | 0.37 |
| ▸ | ACHE | P22303 | 1/20 | 0.36 |
| ▸ | BACE1 | P56817 | 1/20 | 0.36 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 2/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.34 |
| ▸ | CNR2 | P34972 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13162817 | 0.90 | CA12 (0.39) | CCR2ACHEBACE1L3MBTL1POLB | |
| SCHEMBL13634231 | 0.81 | CNR2 (0.50) | ACHEBACE1CNR2 | |
| SCHEMBL13634354 | 0.80 | CCR2 (0.45) | CCR2ACHEBACE1L3MBTL1POLB | |
| SCHEMBL2771166 | 0.75 | MAPK1 (0.42) | L3MBTL1POLBALDH1A1HPGD | |
| SCHEMBL2062569 | 0.74 | L3MBTL1 (0.60) | KCNA5L3MBTL1POLBRXFP1ALDH1A1 | |
| SCHEMBL13162811 | 0.72 | KMT2A (0.48) | TDP1CNR2 | |
| SCHEMBL31432123 | 0.71 | KCNA5 (0.40) | ACHEBACE1KCNA5L3MBTL1POLB | |
| SCHEMBL2916493 | 0.71 | L3MBTL1 (0.55) | KCNA5L3MBTL1POLBRXFP1ALDH1A1 | |
| SCHEMBL24516604 | 0.70 | P2RX7 (0.37) | CCR2ACHEBACE1RXFP1 | |
| SCHEMBL30288828 | 0.70 | P2RX7 (0.37) | CCR2ACHEBACE1RXFP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8304547-B2 | Azolecarboxamide compound or salt thereof | ASTELLAS PHARMA INC. (JP) | 2012-11-06 | — | — | US | disclosed |