SCHEMBL13634358

SCHEMBL13634358

CCCNC(=O)c1cc(CN2CCOCC2)c(C)cc1N

nearest known ligand 0.47

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
CNR2 P34972 12/20 0.47
POLB P06746 1/20 0.44
CNR1 P21554 3/20 0.44
TSHR P16473 1/20 0.43
LMNA P02545 1/20 0.42
KDM4E B2RXH2 1/20 0.41
MAPT P10636 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13162806 0.89 KMT2A (0.55) CNR2POLBTSHRLMNAKDM4E
SCHEMBL13634407 0.81 KMT2A (0.52) TSHRLMNAKDM4EMAPT
SCHEMBL13634231 0.79 CNR2 (0.50) CNR2CNR1KDM4EMAPT
SCHEMBL13634497 0.78 KMT2A (0.61) CNR2POLBTSHRLMNAKDM4E
SCHEMBL13162383 0.77 KMT2A (0.53) POLBLMNAKDM4E
SCHEMBL13634241 0.74 LMNA (0.48) POLBTSHRLMNA
SCHEMBL2771372 0.74 KMT2A (0.53) CNR2POLBLMNAKDM4E
SCHEMBL13634373 0.70 KMT2A (0.57) LMNAMAPT
SCHEMBL31504829 0.70 CYP2C19 (0.58) LMNA
SCHEMBL13162811 0.70 KMT2A (0.48) CNR2CNR1LMNAMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8304547-B2 Azolecarboxamide compound or salt thereof ASTELLAS PHARMA INC. (JP) 2012-11-06 US disclosed