Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.45 |
| ▸ | FGFR2 | P21802 | 1/20 | 0.45 |
| ▸ | FGFR3 | P22607 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.43 |
| ▸ | DRD4 | P21917 | 1/20 | 0.42 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13162753 | 0.90 | ALDH1A1 (0.49) | ALDH1A1KDM4ELMNAFGFR1FGFR2 | |
| SCHEMBL13162755 | 0.89 | ALDH1A1 (0.52) | ALDH1A1KDM4EFGFR1FGFR2FGFR3 | |
| SCHEMBL13634183 | 0.88 | ALDH1A1 (0.49) | ALDH1A1KDM4EFGFR1FGFR2FGFR3 | |
| SCHEMBL2770332 | 0.87 | ALDH1A1 (0.55) | ALDH1A1KDM4EFGFR1FGFR2FGFR3 | |
| SCHEMBL2772464 | 0.86 | ALDH1A1 (0.45) | ALDH1A1KDM4EFGFR1FGFR2FGFR3 | |
| SCHEMBL13638860 | 0.80 | ALDH1A1 (0.45) | ALDH1A1KDM4EFGFR1FGFR2FGFR3 | |
| SCHEMBL13634263 | 0.79 | SIRT6 (0.51) | ALDH1A1KDM4ELMNAHTTSMN1; SMN2 | |
| SCHEMBL2770947 | 0.79 | ALDH1A1 (0.57) | ALDH1A1LMNANPC1RAB9AKMT2A | |
| SCHEMBL13634373 | 0.77 | KMT2A (0.57) | ALDH1A1LMNASMN1; SMN2KMT2AMAPT | |
| SCHEMBL13163950 | 0.77 | MCHR1 (0.55) | KDM4EFGFR1FGFR2FGFR3SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8304547-B2 | Azolecarboxamide compound or salt thereof | ASTELLAS PHARMA INC. (JP) | 2012-11-06 | — | — | US | disclosed |