Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.51 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | HTT | P42858 | 4/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.48 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | BLM | P54132 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL378383 | 0.88 | SIRT6 (0.65) | SIRT6ALDH1A1LMNAHTTSMN1; SMN2 | |
| SCHEMBL13634150 | 0.88 | SIRT6 (0.55) | SIRT6ALDH1A1LMNAHTTSMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL378382 | 0.87 | SIRT6 (0.64) | SIRT6ALDH1A1LMNAHTTSMN1; SMN2 | |
| SCHEMBL495726 | 0.87 | SIRT6 (0.54) | SIRT6ALDH1A1LMNAMAPTMAPK1 | |
| SCHEMBL2771503 | 0.85 | SMN1; SMN2 (0.53) | SIRT6ALDH1A1LMNASMN1; SMN2MAPT | |
| SCHEMBL13161884 | 0.85 | KDM4E (0.52) | SIRT6ALDH1A1LMNAHTTSMN1; SMN2 | |
| SCHEMBL13163915 | 0.84 | ALDH1A1 (0.61) | SIRT6ALDH1A1LMNAHTTSMN1; SMN2 | |
| SCHEMBL13634261 | 0.84 | SIRT6 (0.51) | SIRT6ALDH1A1LMNAMAPTMAPK1 | |
| SCHEMBL15888503 | 0.83 | SIRT6 (0.50) | SIRT6ALDH1A1LMNAHTTSMN1; SMN2 | |
| SCHEMBL13161883 | 0.81 | ALDH1A1 (0.50) | SIRT6ALDH1A1LMNASMN1; SMN2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8304547-B2 | Azolecarboxamide compound or salt thereof | ASTELLAS PHARMA INC. (JP) | 2012-11-06 | — | — | US | disclosed |