Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN9A | Q15858 | 5/20 | 0.41 |
| ▸ | SCN7A | Q01118 | 1/20 | 0.41 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.41 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.40 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.40 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.40 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.39 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.37 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.37 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.37 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.37 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL85215 | 0.78 | OPRM1 (0.44) | SCN9ASCN7ASCN5AOPRM1OPRD1 | |
| SCHEMBL16448465 | 0.77 | OPRM1 (0.41) | SCN9ASCN7ASCN5AOPRM1OPRD1 | |
| SCHEMBL3098890 | 0.76 | RBP4 (0.54) | SCN9ASCN7ASCN5AALDH1A1CYP2D6 | |
| SCHEMBL13073743 | 0.74 | SLC6A9 (0.43) | SCN9ASCN7ASCN5AOPRM1OPRD1 | |
| SCHEMBL16759363 | 0.73 | SLC6A9 (0.46) | OPRM1OPRD1ALDH1A1MEN1KMT2A | |
| SCHEMBL72670 | 0.72 | MEN1 (0.48) | OPRM1OPRD1OPRK1OPRL1ALDH1A1 | |
| SCHEMBL85392 | 0.72 | OPRM1 (0.48) | OPRM1OPRD1OPRK1OPRL1ALDH1A1 | |
| SCHEMBL84788 | 0.72 | OPRM1 (0.44) | OPRM1OPRD1OPRK1OPRL1MEN1 | |
| SCHEMBL14141067 | 0.72 | OPRM1 (0.44) | OPRM1OPRD1OPRK1OPRL1MEN1 | |
| SCHEMBL1122107 | 0.72 | SCN9A (0.47) | SCN9ASCN7ASCN5AOPRM1OPRD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8304547-B2 | Azolecarboxamide compound or salt thereof | ASTELLAS PHARMA INC. (JP) | 2012-11-06 | — | — | US | disclosed |
| US-8304547-B2 | Azolecarboxamide compound or salt thereof | ASTELLAS PHARMA INC. (JP) | 2012-11-06 | — | — | US | disclosed |