Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDK1 | Q15118 | 3/20 | 0.40 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.40 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.40 |
| ▸ | MTOR | P42345 | 1/20 | 0.38 |
| ▸ | F2RL3 | Q96RI0 | 1/20 | 0.34 |
| ▸ | OGA | O60502 | 1/20 | 0.33 |
| ▸ | PIK3CA | P42336 | 5/20 | 0.33 |
| ▸ | PIK3CD | O00329 | 4/20 | 0.33 |
| ▸ | PIK3CG | P48736 | 4/20 | 0.33 |
| ▸ | PIK3CB | P42338 | 3/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | IDH1 | O75874 | 1/20 | 0.33 |
| ▸ | DNM1L | O00429 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | AADAT | Q8N5Z0 | 1/20 | 0.31 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13634284 | 1.00 | PDK1 (0.40) | PDK1PDK2PDK3MTORF2RL3 | |
| SCHEMBL3545517 | 0.85 | PDK1 (0.39) | PDK1PDK2PDK3MTORPIK3CA | |
| SCHEMBL28003161 | 0.84 | MTOR (0.41) | PDK1PDK2PDK3MTORPIK3CA | |
| SCHEMBL16603221 | 0.81 | F2RL3 (0.44) | F2RL3ADORA1 | |
| SCHEMBL3551339 | 0.81 | MTOR (0.37) | PDK1PDK2PDK3MTORPIK3CA | |
| SCHEMBL13634271 | 0.81 | IRAK4 (0.39) | MTOROGAPIK3CAPIK3CDPIK3CG | |
| SCHEMBL13634351 | 0.80 | PDK1 (0.38) | PDK1PDK2PDK3MTOROGA | |
| SCHEMBL3435910 | 0.80 | PDK1 (0.38) | PDK1PDK2PDK3MTOROGA | |
| SCHEMBL13162772 | 0.79 | MTOR (0.40) | PDK1PDK2PDK3MTORPIK3CA | |
| SCHEMBL13162767 | 0.79 | MTOR (0.40) | PDK1PDK2PDK3MTORPIK3CA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8304547-B2 | Azolecarboxamide compound or salt thereof | ASTELLAS PHARMA INC. (JP) | 2012-11-06 | — | — | US | disclosed |