Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.39 |
| ▸ | MTOR | P42345 | 6/20 | 0.38 |
| ▸ | PIK3CA | P42336 | 5/20 | 0.38 |
| ▸ | PIK3R1 | P27986 | 2/20 | 0.38 |
| ▸ | ATR | Q13535 | 5/20 | 0.38 |
| ▸ | PDE4D | Q08499 | 3/20 | 0.38 |
| ▸ | PIK3C3 | Q8NEB9 | 4/20 | 0.36 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.36 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.36 |
| ▸ | ATRIP | Q8WXE1 | 1/20 | 0.36 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.36 |
| ▸ | OGA | O60502 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | RPTOR | Q8N122 | 2/20 | 0.35 |
| ▸ | MLST8 | Q9BVC4 | 2/20 | 0.35 |
| ▸ | PIK3CD | O00329 | 3/20 | 0.35 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.35 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.35 |
| ▸ | RICTOR | Q6R327 | 1/20 | 0.35 |
| ▸ | MAPKAP1 | Q9BPZ7 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24375495 | 0.81 | IRAK4 (0.41) | IRAK4MTORPIK3CAPIK3R1ATR | |
| SCHEMBL13634284 | 0.81 | PDK1 (0.40) | MTORPIK3CAOGAMAPTPIK3CD | |
| SCHEMBL13634272 | 0.81 | PDK1 (0.40) | MTORPIK3CAOGAMAPTPIK3CD | |
| SCHEMBL24375533 | 0.80 | MTOR (0.44) | IRAK4MTORPIK3CAPIK3R1ATR | |
| SCHEMBL13634279 | 0.78 | DNM1L (0.42) | OGA | |
| SCHEMBL28003505 | 0.78 | ATR (0.46) | IRAK4MTORPIK3CAPIK3R1ATR | |
| SCHEMBL21889136 | 0.78 | LMNA (0.61) | IRAK4MTORPIK3CAPIK3R1ATR | |
| SCHEMBL18674655 | 0.76 | LMNA (0.58) | OGAMAPT | |
| SCHEMBL13162764 | 0.76 | MTOR (0.41) | IRAK4MTORATRPDE4DPIK3C3 | |
| SCHEMBL10278349 | 0.76 | IRAK4 (0.51) | IRAK4MTORPIK3CAPIK3C3OGA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8304547-B2 | Azolecarboxamide compound or salt thereof | ASTELLAS PHARMA INC. (JP) | 2012-11-06 | — | — | US | disclosed |