Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LDHA | P00338 | 3/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | PTGER1 | P34995 | 9/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | GALR3 | O60755 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.33 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15888628 | 0.86 | GAA (0.43) | KDM4EALDH1A1GAASMN1; SMN2CYP1A2 | |
| SCHEMBL3559561 | 0.85 | PTGER1 (0.38) | LDHAKDM4EALDH1A1GAASMN1; SMN2 | |
| SCHEMBL13634282 | 0.81 | — | — | |
| SCHEMBL30295682 | 0.80 | ADORA2A (0.43) | LDHAPTGER1CYP1A2 | |
| SCHEMBL29064995 | 0.80 | ADORA2A (0.43) | LDHAPTGER1CYP1A2 | |
| SCHEMBL13162577 | 0.79 | LDHA (0.36) | LDHAKDM4EALDH1A1GAASMN1; SMN2 | |
| SCHEMBL3435910 | 0.77 | PDK1 (0.38) | LDHAKDM4EALDH1A1GAASMN1; SMN2 | |
| SCHEMBL13634351 | 0.77 | PDK1 (0.38) | LDHAKDM4EALDH1A1GAASMN1; SMN2 | |
| SCHEMBL13638810 | 0.76 | — | — | |
| SCHEMBL3541650 | 0.74 | RAB9A (0.45) | ALDH1A1GAASMN1; SMN2CYP1A2CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8304547-B2 | Azolecarboxamide compound or salt thereof | ASTELLAS PHARMA INC. (JP) | 2012-11-06 | — | — | US | disclosed |
| US-8304547-B2 | Azolecarboxamide compound or salt thereof | ASTELLAS PHARMA INC. (JP) | 2012-11-06 | — | — | US | disclosed |