Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR2 | Q8TDS4 | 6/20 | 0.33 |
| ▸ | PPARG | P37231 | 2/20 | 0.32 |
| ▸ | PPARA | Q07869 | 1/20 | 0.32 |
| ▸ | THRA | P10827 | 1/20 | 0.32 |
| ▸ | RARA | P10276 | 1/20 | 0.30 |
| ▸ | RARB | P10826 | 1/20 | 0.30 |
| ▸ | RARG | P13631 | 1/20 | 0.30 |
| ▸ | CES1 | P23141 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15888647 | 0.86 | NLRP3 (0.41) | KDM4E | |
| SCHEMBL2771127 | 0.86 | CFTR (0.37) | HCAR2PPARG | |
| SCHEMBL13162339 | 0.82 | PPARG (0.34) | PPARGPPARAKDM4E | |
| SCHEMBL18739885 | 0.79 | PLA2G4A (0.39) | HCAR2CES1HCAR3 | |
| SCHEMBL13634371 | 0.77 | — | — | |
| SCHEMBL13162319 | 0.77 | CES1 (0.33) | CES1 | |
| SCHEMBL2077461 | 0.76 | CYP1A2 (0.41) | KDM4E | |
| SCHEMBL15888557 | 0.73 | CYP1A2 (0.38) | PPARGPPARAKDM4E | |
| SCHEMBL13634202 | 0.72 | MEN1 (0.38) | HCAR2RARARARBRARGKDM4E | |
| SCHEMBL3436754 | 0.71 | HPGD (0.40) | KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2206707-B1 | AZOLECARBOXAMIDE COMPOUND OR SALT THEREOF | ASTELLAS PHARMA INC (JP) | 2014-07-23 | — | — | EP | disclosed |
| US-8304547-B2 | Azolecarboxamide compound or salt thereof | ASTELLAS PHARMA INC. (JP) | 2012-11-06 | — | — | US | disclosed |
| US-8304547-B2 | Azolecarboxamide compound or salt thereof | ASTELLAS PHARMA INC. (JP) | 2012-11-06 | — | — | US | disclosed |