Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LIPG | Q9Y5X9 | 8/20 | 0.41 |
| ▸ | LIPC | P11150 | 2/20 | 0.41 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.40 |
| ▸ | TTR | P02766 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 4/20 | 0.36 |
| ▸ | RAB9A | P51151 | 4/20 | 0.36 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.33 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.33 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.33 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.33 |
| ▸ | ACACB | O00763 | 1/20 | 0.33 |
| ▸ | LPL | P06858 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13162581 | 0.91 | TTR (0.39) | LIPGLIPCTTRHSD11B1IRAK4 | |
| SCHEMBL13638873 | 0.90 | LIPG (0.46) | LIPGLIPCTTRIRAK4ACACB | |
| SCHEMBL13634332 | 0.84 | SCD5 (0.39) | TTRIRAK4ACACB | |
| SCHEMBL3436269 | 0.83 | HCRTR1 (0.35) | LIPGTTRLMNAIRAK4HCRTR1 | |
| SCHEMBL20801175 | 0.80 | ADORA2A (0.39) | TTRIRAK4 | |
| SCHEMBL15888574 | 0.79 | HCRTR1 (0.42) | LIPGLIPCIRAK4HCRTR1HCRTR2 | |
| SCHEMBL20801224 | 0.79 | IRAK4 (0.39) | TTRIRAK4 | |
| SCHEMBL15888551 | 0.79 | HCRTR1 (0.44) | TTRLMNANPC1RAB9AIRAK4 | |
| SCHEMBL16896321 | 0.79 | TTR (0.36) | LIPGTTRIRAK4HCRTR1HCRTR2 | |
| SCHEMBL18207856 | 0.79 | TTR (0.36) | LIPGTTRIRAK4HCRTR1HCRTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8304547-B2 | Azolecarboxamide compound or salt thereof | ASTELLAS PHARMA INC. (JP) | 2012-11-06 | — | — | US | disclosed |